LauraPasin (@laura_pasin) 's Twitter Profile
LauraPasin

@laura_pasin

ID: 937653421

calendar_today09-11-2012 19:57:54

372 Tweet

60 Followers

172 Following

San Raffaele Anesthesia and Intensive Care (@sranesthesiaicu) 's Twitter Profile Photo

🫀ANESTHETIC MYOCARDIAL PROTECTION resurrection? Dozens of colleagues and studies worldwide found a cardioprotective effect of volatile agents in laboratory, animal and human studies over the last decades. We re-analyzed our large #MYRIADTrial ➡️ jcvaonline.com/article/S1053-… #FOAMcc

🫀ANESTHETIC MYOCARDIAL PROTECTION resurrection?

Dozens of colleagues and studies worldwide found a cardioprotective effect of volatile agents in laboratory, animal and human studies over the last decades.

We re-analyzed our large #MYRIADTrial ➡️ jcvaonline.com/article/S1053-… #FOAMcc
San Raffaele Anesthesia and Intensive Care (@sranesthesiaicu) 's Twitter Profile Photo

LET’S REDUCE TRANSUSION BY 20% WITH #TRANEXAMIC acid #TXA 1/ We helped PHRI.ca Population Health Research Institute 🇨🇦 in conducting the #POISE3 #RCT published in the NEJM and presented #ACC22 also #mortality is reduced by 10% in this NEJM #RCT on #tranexamic acid. This is probably the most important finding

LauraPasin (@laura_pasin) 's Twitter Profile Photo

Proud to join Frontiers Anesthesiology as Associate Editor. With an amazing editorial team, this new journal will help shape the future of anesthesiology. Find out more: frontiersin.org/journals/anest…

Proud to join <a href="/FrontiersIn/">Frontiers</a> Anesthesiology as Associate Editor. With an amazing editorial team, this new journal will help shape the future of anesthesiology. Find out more: frontiersin.org/journals/anest…
Giovanni Landoni, MD (@giovannilandoni) 's Twitter Profile Photo

This article had large media coverage in Italy, was poorly interpreted, and has 1 dangerous message YES non-steroideal antinflammatory agents are ok for patients at home (minor benefits) NO! corticosteroids are dangerous and should not be prescribed at home (increase mortality)

This article had large media coverage in Italy, was poorly interpreted, and has 1 dangerous message

YES
non-steroideal antinflammatory agents are ok for patients at home (minor benefits)

NO!
corticosteroids are dangerous and should not be prescribed at home (increase mortality)
Giovanni Landoni, MD (@giovannilandoni) 's Twitter Profile Photo

YES! it was 2013 when we LauraPasin Alberto Zangrillo published a letter in the NEJM suggesting that #Glutamine supplementation is detrimental for survival of critically ill patients according to multicenter #RCT pubmed.ncbi.nlm.nih.gov/23902499/

YES! it was 2013 when we <a href="/Laura_Pasin/">LauraPasin</a> <a href="/azangrillo/">Alberto Zangrillo</a> published a letter in the <a href="/NEJM/">NEJM</a> suggesting that #Glutamine supplementation is detrimental for survival of critically ill patients according to multicenter #RCT 
pubmed.ncbi.nlm.nih.gov/23902499/
San Raffaele Anesthesia and Intensive Care (@sranesthesiaicu) 's Twitter Profile Photo

Propofol may increase mortality in ICU and perioperative settings🚨 Our new meta-analysis documented statistically significantly higher mortality in the #propofol group than control group Let's go into depth about this provocative result 🧵/7 🔗ccforum.biomedcentral.com/articles/10.11… #FOAMcc

Propofol may increase mortality in ICU and perioperative settings🚨

Our new meta-analysis documented statistically significantly higher mortality in the #propofol group than control group

Let's go into depth about this provocative result 🧵/7

🔗ccforum.biomedcentral.com/articles/10.11… #FOAMcc
San Raffaele Anesthesia and Intensive Care (@sranesthesiaicu) 's Twitter Profile Photo

🚫 DON’T use glucocorticoids in oxygen-free #COVID19 pts Just published NEJM Evidence   Guidelines are against glucocorticoids in pts not on O2 but effect on survival remains unclear   Our meta-analysis found that glucocorticoids increase mortality 🔗eviden.cc/3MnrDSA 1/5

🚫 DON’T use glucocorticoids in oxygen-free #COVID19 pts

Just published <a href="/NEJMEvidence/">NEJM Evidence</a>
 
Guidelines are against glucocorticoids in pts not on O2 but effect on survival remains unclear
 
Our meta-analysis found that glucocorticoids increase mortality

🔗eviden.cc/3MnrDSA 1/5
Alberto Zangrillo (@azangrillo) 's Twitter Profile Photo

Meta-Analysis of Glucocorticoids for Covid-19 Patients Not Receiving Oxygen | NEJM Evidence evidence.nejm.org/doi/full/10.10…

Stefano Fresilli (@sfresilli) 's Twitter Profile Photo

Our latest manouscript sheds new light on treating hospitalized #COVID19 patients not on oxygen therapy! According to our study sistemic glucocordicoids are detrimental in this setting. 🚨 Read our findings in NEJM Evidence and help spread the word! 📢 #research #coronavirus🦠

Alessandro Pruna, MD (@alessanro_pruna) 's Twitter Profile Photo

‼️Going deep into the problem ⚠️Is propofol detrimental for survival❓ Comments and reflection on propofol and survival MA with the authors: Me and 小谷祐樹 Yuki Kotani|集中治療医 Intensivist 👉ccforum.biomedcentral.com/articles/10.11… ITACTAIC meet the authors TODAY 6.00pm 🔗FREE link itacta.org #FOAMcc

Critical Care (@crit_care) 's Twitter Profile Photo

#CritCare #OpenAccess #Propofol may reduce survival in perioperative and critically ill patients. Read the full article: rdcu.be/c9UU8 Jean-Louis Vincent ISICEM #FOAMed #FOAMcc

#CritCare #OpenAccess

#Propofol may reduce survival in perioperative and critically ill patients.

Read the full article: rdcu.be/c9UU8

<a href="/jlvincen/">Jean-Louis Vincent</a> <a href="/ISICEM/">ISICEM</a> #FOAMed #FOAMcc
NEJM Evidence (@nejmevidence) 's Twitter Profile Photo

“…our meta-analysis shows that administering glucocorticoids in hospitalized patients with Covid-19 not receiving oxygen is likely associated with worse clinical outcomes.” Full study: eviden.cc/3MnrDSA #IDTwitter #ARDS #CriticalCare

Giovanni Landoni, MD (@giovannilandoni) 's Twitter Profile Photo

A nice NEJM Evidence editorial on our article on mortality increase when using #glucorticoids in #covid19 who are not receiving #oxygen x.com/NEJMEvidence/s… “...under some circumstances, randomized controlled trials can become infeasible as evidence accrues (e.g.,

A nice <a href="/NEJMEvidence/">NEJM Evidence</a> editorial on our article on mortality increase when using #glucorticoids in #covid19 who are not receiving #oxygen
x.com/NEJMEvidence/s…

“...under some circumstances, randomized controlled trials can become infeasible as evidence accrues (e.g.,
Society of Critical Care Anesthesiologists (@socca_critcare) 's Twitter Profile Photo

In this meta-analysis by Covello, LauraPasin, Giovanni Landoni, MD, and others in NEJM Evidence, steroids were associated with increased mortality when administered to COVID-19 patients not requiring oxygen. #steroids #COVID19 buff.ly/3Vu4kZI

In this meta-analysis by Covello, <a href="/Laura_Pasin/">LauraPasin</a>, <a href="/giovannilandoni/">Giovanni Landoni, MD</a>, and others in <a href="/NEJMEvidence/">NEJM Evidence</a>, steroids were associated with increased mortality when administered to COVID-19 patients not requiring oxygen. #steroids #COVID19 

buff.ly/3Vu4kZI
San Raffaele Anesthesia and Intensive Care (@sranesthesiaicu) 's Twitter Profile Photo

We've just presented and published a multicenter RCT at #CCR23 and in JAMA! Continuous vs Intermittent Meropenem Administration in Critically Ill Patients with Sepsis: The #MERCYtrial! 🔗 jamanetwork.com/journals/jama/… This 🧵 will explain the study in detail /11 #FOAMcc

We've just presented and published a multicenter RCT at #CCR23 and in <a href="/JAMA_current/">JAMA</a>!

Continuous vs Intermittent Meropenem Administration in Critically Ill Patients with Sepsis: The #MERCYtrial!

🔗  jamanetwork.com/journals/jama/…

This 🧵 will explain the study in detail /11

#FOAMcc