The gut #microbiome fosters the absorption of #tacrolimus through the transcriptional downregulation of #ABCB1 aka the Pglycoprotein. Video Abstract🎬With @DegraeveAlA and Laure Elens, made by Research Square 👀Full article available here rdcu.be/df9YA

🪘Open academic position in the field of Chemistry and Pharmacological Characterization of Drugs from Biological Sources at UCLouvain ! shorturl.at/dnqMV . Teaching in pharmacy, Research at Louvain Drug Research Institute. Do not hesitate to apply !

Stay tune to learn more about #cancercachexia research and discover the communication talents of our finalists!

3..2..1..ACTION!📽️🎞️#CCS2023CommunicationAward nominee Chandler Callaway shows that liver metastases from colorectal cancer trigger pro-atrophic signaling pathways and upregulate gap junction and adhesion signaling molecules, likely contributing to exacerbated #cachexia. 🙌

Here we are to the 2nd #CCS2023CommunicationAward nominee, Brittany Counts, who investigated cell specific transcription and microenvironment in cachexia by snRNAseq and revealed that transcriptionally diverse myonuclei are present prior to muscle wasting in #PDAC #cachexia. 📽️🎞️

Ready for our 3rd video? 📽️ #CCS2023CommunicationAward nominee Lisa Duff proposes to use preclinical PET imaging to identify differences in metabolic pathways within the body, thus representing a novel methodology for quantitative characterization of cancer #cachexia. 🎬

It's time for our fourth video...!🎬 #CCS2023CommunicationAward nominee Aneesha Dasgupta sheds light on the role of histamine as a new (and overlooked) wasting-associated metabolic pathway that could represent a potential therapeutic avenue for cancer #cachexia.

🎬#CCS2023CommunicationAward finalist Josh Huot, PhD, CSCS shows that tumor FGF21 triggers hepatic release of IGFBP1, which in turn drives muscle and bone loss. These data support novel strategies to counteract the tumor-liver-muscle axis in the treatment of #cancercachexia👌

In the last #CCS2023CommunicationAward video 🎬Fran uses global gene expression analyses by RNAseq to compare the transcriptional landscape of skeletal muscle in multiple pre-clinical models of cancer #cachexia at early and late stages. Good luck to our finalists! 🏆

Can you help us?😊(retweet, like) We are looking for a highly motivated and talented candidate for our fully-funded #PhD position in Precision #Nutrition, #Metabolomics and #Bioinformatics! 🥦👩‍🔬 Join us in the ♥️ of Copenhagen Deadline: Nov 5, 2023 employment.ku.dk/phd/?show=1602…

NextGen scholars at #CCS23. The future is bright! 🤩🤩🤩

Save the date! The 8th Cancer Cachexia Conference, Sept 25-27, 2025.

PhD Studentship in the HORIZON-MSCA-2022-DN Doctoral Network “CLEAR” | EURAXESS euraxess.ec.europa.eu/jobs/190023

The Education Committee of the Cancer Cachexia Society Society invites you to our seminar on March 13, 2024 at 12 PM EDT with Danna M. Breen, PhD, Medicine Research Unit at Pfizer, Cambridge, MA, USA. Seminars are open to everyone, please share! See cancercachexiasociety.org to register.

We're looking for a Research Associate to join our new IMIBirmingham team! Note, this is not a postdoc role; instead, we're seeking someone with a strong background in #microbiology & #microbiome research to support our team in a senior tech capacity 👇🦠 jobs.ac.uk/job/DGD732/res…

Congratulations ! This work demonstrates that tumoral acidosis can promote adipose tissue wasting through the release of soluble factors, highlighting a previously unknown link between tumoral acidosis and adipose tissue wasting at distance of the tumor. @televie UCLouvain Recherche-Research

The Education Committee of the Cancer Cachexia Society Society invites you to our seminar on May 15 at 12:00 pm EDT with Dr. Anne-Catherine Maurin, PhD, INRAE/Clermont-Auvergne University, France. Seminars are open to everyone, please share! See cancercachexiasociety.org to register.

📢 Our team is hiring a postdoctoral fellow with expertise in #muscle metabolism and physiology 💪 to work on the gut-muscle axis in cachexia. More info and how to apply on Euraxess lnkd.in/eZ-Axf4v. Deadline for application July 10 ! 🙏 RT #postdocposition #uclouvain

Tumoral acidosis induces #adipocyte lipolysis, contributing to #adiposetissue depletion in #cancer #cachexia. Targeting #acidosis may offer new cachexia treatments. 👩‍🔬👨‍🔬Laure Bindels @UCLouvain_be 🔗sciencedirect.com/science/articl…

Join us in Torino in Sept 25 for exciting science on #cancer #cachexia !