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Super happy to see my PhD work with @martens_sascha out in The EMBO Journal. A big thanks to everyone involved and also to EMBO Press for the smooth revision process! #Autophagy #MaxPerutzLabs #VBC For more infos see the paper & my previous tweetorial: embopress.org/doi/full/10.10…

At age 47 Sheenagh was diagnosed with Parkinson’s disease. There is no cure, yet. Your donation today can accelerate life-saving medical research for Parkinson’s disease and other debilitating conditions. wehi.edu.au/support-us/don… #Parkinsons #YouAreTheCure

New paper out! #AMPK regulates #ULK1 to balance #mitophagy of functional vs dysfunctional mitochondria in Molecular Cell. Great work from authors, especially Marianna Longo Aniketh Bishnu and collaborators @Kei_Sakamoto Carol MacKintosh. See it here: tinyurl.com/AMPK-ULK

Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui Zhicheng Cui | 崔志成 using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ Gennaro Napolitano, A. Esposito, and A. Ballabio.

We have a PhD position available to study neuronal functions of autophagy and endocytosis.

It was great to have nearly 120 scientists gather for 20th anniversary Biochemical Society Aligning Science Across Parkinson’s meeting in London to mark discovery of #PINK1 mutations in Parkinson's patients by Nick Wood MovementDisordersUCL UCL Brain Sciences in 2004. 🙏also to Cure Parkinson's Parkinson UK

Did we conceive the structure of neurons incorrectly all these years? nature.com/articles/s4159… Nature Neuroscience not smooth, cylindrical strands but a string of pearls? it's controversial science.org/content/articl… News from Science Science Magazine

Excited to share our latest preprint on bioRxiv: "The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro". biorxiv.org/content/10.110…

Excited to reveal specific reactive oxygen species as sentinel molecules that control localized protein degradation at #mitochondria to adjust the electron transport chain, with many implications for ROS in development and disease. UC Berkeley Molecular Therapeutics Initiative cell.com/molecular-cell…

📢📢New work from Dr Linh Dang in my group - analysis of physiological human autophagic flux in leukocytes. Surprises related to ageing, sex effects, and nutrient sensing! SAHMRI #autophagy #aging Cell-type specific autophagy in human leukocytes biorxiv.org/content/10.110…

NEW #Preprint on #ATG8 specialization in #autophagy in #plants: biorxiv.org/content/10.110… A short 🧵

Looking for reviewers before Christmas

Excited that our review: "Exercise as Mitochondrial Medicine: How Does the Exercise Prescription Affect Mitochondrial Adaptations to Training?" will soon be published in ANNUAL REVIEW OF PHYSIOLOGY with Martin Picard & Matt Lee

This paper is a stark reminder for why it is so important to innovate in drug discovery against neurodegenerative diseases now. Molecular Therapeutics Initiative nature.com/articles/s4159…