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Here suppression of the DMV–vagus–jejunum axis controls intestinal fat absorption by shortening the length of microvilli with therapeutic potential for #weightloss nature.com/articles/s4158…

New preprint from kuldeep shrivastava looking at how BNST and lateral hypothalamic glutamatergic neurons coordinate reward seeking based on energy state. researchsquare.com/article/rs-520…

Analysis of vagal sensory activity identifies Fgf3 as a vagal sensory-derived metabolic factor within the pancreas that controls pancreatic β-cell activity and GSIS #insulin Developmental Cell cell.com/developmental-…

Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons biorxiv.org/cgi/content/sh… #biorxiv_neursci

Check out our new work for Center for Eating and feeding Disorders Research! Using the register data of 17 million Danes and Swedes we were able to estimate the genetic correlation between multiple eating- and psychiatric disorders. We found new correlations with autism and OCD! medrxiv.org/content/10.110…

This wonderful event is scheduled right before SfN 2025 in San Diego and is open to the public!

Tetanus on demand! (not for bioweapons, but for neuroscience research) Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release. To harness this toxicity and use it as a beneficial tool for

VTA dopamine-releasing neurons encode palatability and control the consummatory phase of eating dependent on the specific timing of their activity, actions suppressed by activation of GLP-1R signaling during palatable food consumption #weightloss #obesity science.org/doi/10.1126/sc…

I’m so excited to share our preprint on how brainstem neurons sense and integrate multiple body signals during food consumption. We imaged 1000s of neurons across the lateral parabrachial nucleus (LPBN) in behaving mice. biorxiv.org/content/10.110…

Studies in mice of CNS GLP-1R circuits reveals that state-dependent synaptic regulation by GLP-1 in PVNGLP-1R→DVC descending circuits is important for energy homeostasis Nature Metabolism nature.com/articles/s4225…

State-dependent central synaptic regulation by GLP-1 is essential for energy homeostasis go.nature.com/3HrcD5J

GLP-1-mediated synaptic plasticity in feeding regulation is modulated by energy state go.nature.com/3TgUkTf

A nice write up about the new work coming out of the Rutgers Center for NeuroMetabolism rutgers.edu/news/two-rutge…

Great opportunity! Highly recommend.

The biology of eating disorders nature.com/articles/s4158…

New paper from the Laboratory Neurobiology of Appetite ⁦Cinvestav⁩ Congratulations to Axl Lopez in developing the first DeepLabCut model to measure stereotypy in Rats! Sex-specific effects of appetite suppressants on stereotypy in rats | PLOS One journals.plos.org/plosone/articl…

📣 Our protocol to generate brain #organoids from #StemCell derived Single Neural Rosettes 👇

"As a scientist, I’m not much of a believer in fate, but it does seem like the universe had a plan for me." Excellent piece about #TemertyMed's Dr. Daniel J Drucker and his groundbreaking work and career. @TorontoLife bit.ly/44dLpZb