Most venous #thrombosis #VTE pts ▶️treated +DOACs 💊 In new #JTHiC case-based discussion for DOAC interruption perioperatively in pts receiving VTE anticoagulation. #JTHiC @connors_md Jonathan Berry Rushad Patell Jeff Zwicker, MD BIDMC Hematology/Oncology Fellowship Memorial Sloan Kettering Cancer Center bit.ly/3Y5dpID

📢Alert! Women with #superficial vein #thrombosis (SVT) in #pregnancy had a 10.4% risk of having #VTE in that same pregnancy or postpartum period. That is a huge risk justifying treatment of #SVT. The Lancet Haematology Free download until May 13, 2023 authors.elsevier.com/c/1goj-8MsWYFu…

Now in a large population-based cohort - pts w/ ALK+ #lungcancer at a significantly higher risk for #VTE vs nonALK #nsclc. Awareness is 🗝️! do we need +data or start using prphl💊? academic.oup.com/oncolo/advance…

If cerebral vein thrombosis (#CVT) fails to recanalise after 3-6 months, the risk of CVT recurrence is 8.8x higher. Suggests that anticoagulation length should vary depending on recanalisation status. Free PDF in RPTH. tinyurl.com/hzk2f864

Now available: Podcast🎧🗣️ jacc.org/do/10.1016/pod… Editorial 📄 jacc.org/doi/10.1016/j.…

Patients with cancer-associated #thrombosis and #thrombocytopenia have high risks of recurrent VTE and major bleeding. Future RCTs such as the START trial (NCT05255003) are needed! authors.elsevier.com/c/1h4w5_17tKUx… in Thrombosis Research Marc Carrier Aurélien Delluc

📣Publication alert: finally published in The Lancet , the ALIFE2 trial. So thankful to all women who participated and all colleagues who joined the study. LMWH does NOT improve live birth in women with #thrombophilia and #recurrent miscarriage. thelancet.com/pb-assets/Lanc…

Severity of ICH was similar for patients on DOACs and LMWH Avi Leader #ISTH2023

Dr. Avi Leader presented the second phase of the ABC study which reported on the 65 patients with ICH on anticoagulation during the study. Majority of ICH are overt and intramural. VTE is frequent after ICH. No clear association between AC management and VTE post-ICH. #ISTH2023

LIVE NOW: Avi Leader #ISTH2023 SOA Address: Arterial thrombosis is ↑ in cancer & under-treated. Challenges in treatment include ↑ bleeding, drug-drug interactions & ↓ platelets. Cancer-specific #thrombosis management shown ⬇️ in #CoagCapsule. isth.org/23Capsules

Dr. Avi Leader providing a great overview of arterial thromboembolism (ATE) in patients with cancer. ATE are often neglected in CAT literature. ATE is common in new diagnosed patient and associates with higher mortality! #ISTH2023

A Fib is common in patient with cancer. These patients are at higher risk if ATE but also at high risk of bleeding is also high. Good guidance are available to help clinicians #ISTH2023 Avi Leader

Pts with cancer are at ⬆️ risk of ATE including IS 🧠 Cancer is a known cause of ESUS. Tx of ESUS in cancer is not well defined. Pts with cancer and ESUS have a ⬆️ risk of recurrent stroke with DOACs or ASA Future RCTs are needed (and planned) to guide tx Avi Leader #ISTH2023

🚨Great guidance paper from Anna Falanga & Avi Leader et al. to help with management of these challenging situations. pubmed.ncbi.nlm.nih.gov/35924068/

What is the risk of ICH in patients using DOAC vs LMWH with primary or metastatic brain tumor? Avi Leader presents the ABC study at #ISTH2023

Avi Leader presents results from the ABC registry for AC with DOAC or LMWH in brain tumors. - 🚫diff in rate of spontaneous (not caused by surgery) ICH between DOAC vs LMWH (but numerically ⬇️ with DOAC) #ISTH2023

#Match2024 & #FellowMatch Memorial Sloan Kettering Cancer Center MSK Department of Medicine NRMP® Hem-Onc Fellows Network I am happy to announce the MSKCC Hematology Focused Fellowship track! mskcc.org/hcp-education-…

New 2023 ACR/EULAR Antiphospholipid Syndrome (APS) Classification Criteria are out! Patients need at least 3 points each from the clinical and lab domains (See below) to be classified as having APS. This will be very useful to clinicians :) acrjournals.onlinelibrary.wiley.com/doi/full/10.10… ISTH

VTE patients with brain cancer have an increased risk for intracranial bleeding during anticoagulation Another study by the #RIETEregistry team, leaded by Cecilia Becattini and Michela Giustozzi

Simple intervention that makes sense! STRATUS #RCT trial led by Dr Deborah Siegal and PHRI.ca Population Health Research Institute 🇨🇦 in JAMA reported that using small-volume tubes for 🩸 collection⬇️ RBC transfusion in ICU patients. ↔️ in insufficient specimens. jamanetwork.com/journals/jama/…