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Seyedsayamdost and colleagues from Princeton Chemistry show that the biosynthesis of Streptococcal bicyclostreptins involves cyclization reactions mediated by radical SAM enzymes. Free to read link at rdcu.be/cTumy

Vitamin B3 Triggers #Biosynthesis of Secondary Metabolite Dormancy Signals in Streptococcus suis by Brett C. Covington and Mohammad R. Seyedsayamdost at Princeton Chemistry Princeton MolBio in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

Amazing visit to Bradley Moore lab Scripps Institution of Oceanography UC San Diego hosted by Leah Bushin―exciting scientific discussions crowned by an ocean swim from the shore to the tip of the Ellen Browning Memorial Pier (I got the official Scripps t-shirt as a prize!) 🏊🏻‍♂️

Another year and another fun #scrippspierswim with our friends from GerwickLab Pieter Dorrestein Jack A Gilbert (he/him/his) @lab_lyons Amro Hamdoun Eric Allen, Bill Fenical & Todd Michael labs. Thanks MooreLabSIO & see you next year Scripps Institution of Oceanography for the 18th annual

Bioinformatic Atlas of Radical SAM Enzyme-Modified #RiPP Natural Products Reveals an Isoleucine–Tryptophan Crosslink by Kenzie A. Clark and Mohammad R. Seyedsayamdost at Princeton Chemistry Princeton MolBio in J. Am. Chem. Soc. pubs.acs.org/doi/10.1021/ja…

Congrats to my friend and former colleague Kenzie on this fantastic work!

Wonderful spending the day with so many friends, colleagues, students, staff, and family at yesterday's 19th Annual #Scrippspierswim at Scripps Institution of Oceanography. One of my favorite days each year!!

Tired of low heterologous biosynthesis yields? Try GrowBio to rapidly make g/l bioproduction. Just give synthetic cells a reason to make your favorite compound like the octopus pigment xanthommatin. Led by Leah Bushin and out at biorxiv.org/content/10.110…