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Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies dlvr.it/Rv2TpX

Please RT: DNA repair peeps! The Gordon Research Conference on Mammalian DNA repair with the associated GRS has been moved to start on October 30th and it will be an in person meeting in Ventura,CA. We promise to have a great line up and already have a star keynote in Gaëlle Legube lab Chromatin Repair

Glad to share our latest paper on a new role of RNA in homologous recombination. Thanks to members of my team and our collaborators! RNA transcripts stimulate homologous recombination by forming DR-loops | Nature nature.com/articles/s4158…

Our lab is expanding and we're recruiting postdoctoral fellows to study ubiquitin-dependent control mechanisms of gene regulation at MGH/Harvard Medical Please RT! ohlabs.org/apply

A very nice review by Yasuhara and Lee Zou on: Impacts of chromatin dynamics and compartmentalization on DNA repair sciencedirect.com/science/articl…

Why are #PARPInhibitors so effective on #BRCA-mutant cancer cells? Dr. Lee Zou (Lee Zou) and his colleagues found that PARP inhibitors work by creating gaps in tumor cell DNA that persist through multiple cell cycles, ultimately leading to cell death. 🔎 bit.ly/3ACPGUr

Online Now: A basal-level activity of ATR links replication fork surveillance and stress response dlvr.it/S6l6sc

The final program for the DNA Repair GRC 2021 is posted. Lee Zou and GRC prepared an awesome program and new COVID-19 protocols to stay safe. Thank you to all the participants for their support. Can’t wait to meet in-person again. Register by Oct 3! grc.org/mammalian-dna-…

BREAKING NEWS: The 2021 #NobelPrize in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”

We are deeply saddened by the loss of David Livingston, MD. He was a towering figure in cancer research who changed the way research is done and was an inspiring mentor to many. Our hearts go out to his family, friends, and colleagues. dana-farber.org/newsroom/news-…

Started the Gordon Research Conferences GRS on Mammalian DNA Repair with a beautiful talk from @AgnelSfeir ! Excited for all the science to come!

The Mass General Cancer Center has launched a faculty search for an Assistant Professor. Candidates from groups traditionally underrepresented in scientific research are strongly encouraged to apply here: bit.ly/3CiwhIW Deadline: 12/1 #MGHCC

Followed by GRC on Genomic Instability, DNA repair and Human diseases; lined up with exciting speakers!! Organized by Lee Zou Michael Huen Agata Smogorzewska and Kyungjae Myung!! Pls RT.

Hallmarks of DNA replication stress Lee Zou dlvr.it/SSZ8Tq

Condensates induced by transcription inhibition localize active chromatin to nucleoli dlvr.it/SW3mNS

It is official! We look forward to welcoming our new chair Dr. Lee Zou to Duke and PCB at the beginning of next year.

Online Now: TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch dlvr.it/SbMsLc

Tenure-track Faculty Position, Cancer Biology job with Duke Pharmacology and Cancer Biology | 12805221 nature.com/naturecareers/…

Registration deadline is approaching for the conference on "Transcription and Genome maintenance" ! There are slots for selected talks! Register before May6th insb.cnrs.fr/fr/transcripti…

Online Now: Unprocessed genomic uracil as a source of DNA replication stress in cancer cells dlvr.it/T69bhR