Julien Lefranc (@lefrancju) 's Twitter Profile
Julien Lefranc

@lefrancju

#Medchem @merckgroup former @bayerpharma interested in #cancer #kinaseinhibitors #degraders only personal views Reviewer @drughunter

ID: 931798721808957440

linkhttps://orcid.org/0000-0002-2116-9425 calendar_today18-11-2017 08:18:22

932 Tweet

920 Followers

602 Following

London Lab (@london_lab) 's Twitter Profile Photo

Deadline is coming up for nomination to the EFMC 2024 awards, 31 Jan 2024: efmc.info/awards be sure to nominate someone you admire! 🏆

Kevin Lam (@klchemistry) 's Twitter Profile Photo

RT, please 😀We are starting the interviews next month! Still time to apply to join our ⚡ElectraTeam⚡! One PhD in collaboration with GSK PdCyclist/ Darren Poole: findaphd.com/phds/project/g… and another one funded by the The Leverhulme Trust: findaphd.com/phds/project/l… #RealTimeChem

RT, please 😀We are starting the interviews next month! Still time to apply to join our ⚡ElectraTeam⚡! One PhD in collaboration with <a href="/GSK/">GSK</a> <a href="/PdCyclist/">PdCyclist</a>/
<a href="/DPSynthChemist/">Darren Poole</a>: 
findaphd.com/phds/project/g… and another one funded by the <a href="/LeverhulmeTrust/">The Leverhulme Trust</a>: findaphd.com/phds/project/l… #RealTimeChem
Ingo Hartung (@hartungingo) 's Twitter Profile Photo

We have an open position for a postdoc in our Medicinal Chemistry & Drug Design department Merck: If you are equally excited about chemistry automation and about applying synthetic chemistry to answer biological questions, check out this highly attractive opportunity!

We have an open position for a postdoc in our Medicinal Chemistry &amp; Drug Design department <a href="/merckgroup/">Merck</a>: If you are equally excited about chemistry automation and about applying synthetic chemistry to answer biological questions, check out this highly attractive opportunity!
drug hunter (@drughunter_com) 's Twitter Profile Photo

Molecules of the Month – Feb. 2024 Actelion revealed the discovery story of nivasorexant, a selective orexin-1 receptor antagonist, which completed a Ph. II clinical trial in binge-eating disorder. Check out our other top molecules from Feb.! Article | drughunters.com/3vbzEDY

Molecules of the Month – Feb. 2024

Actelion revealed the discovery story of nivasorexant, a selective orexin-1 receptor antagonist, which completed a Ph. II clinical trial in binge-eating disorder.

Check out our other top molecules from Feb.!

Article | drughunters.com/3vbzEDY
Guillaume Laconde (@glaconde34) 's Twitter Profile Photo

🔥🔥“TPD one-day Thematic meeting” in Paris (SANOFI) May 30th 2024 Société de Chimie Thérapeutique : register open bit.ly/4arCfZd Dan Nomura Dr. M. Schroeder Ester Morreale Prof. N. Thomä Ivan Đikić Dr. M. Koegl Dr. S. Jegham Dr. K. McAulay Prof. A.-S. Voisin-Chiret

🔥🔥“TPD one-day Thematic meeting” in Paris (SANOFI) May 30th 2024 <a href="/SCT_asso/">Société de Chimie Thérapeutique</a> : register open  bit.ly/4arCfZd
<a href="/DanNomura/">Dan Nomura</a>
Dr. M. Schroeder
<a href="/fmorreale_ester/">Ester Morreale</a>
Prof. N. Thomä
<a href="/iDikic2/">Ivan Đikić</a>
Dr. M. Koegl
Dr. S. Jegham
Dr. K. McAulay
Prof. A.-S. Voisin-Chiret
Bismuto Lab (@bismutolab) 's Twitter Profile Photo

Come and join us, what are you waiting for?! We have a fully funded PhD position Rheinische Friedrich-Wilhelms-Universität Bonn on Sb- and Bi-luminescent compounds🧪. The deadline is April 24, interested candidate should send the application (cover letter and CV) to [email protected]

Guillaume Laconde (@glaconde34) 's Twitter Profile Photo

There is still time to register for the Thematic meeting from Société de Chimie Thérapeutique: Targeted Protein Degradation Gentilly Sanofi en France (Paris) with a fantastic program. You can click under the following link sct-asso.fr/tpdmeeting

There is still time to register for the Thematic meeting from <a href="/SCT_asso/">Société de Chimie Thérapeutique</a>: Targeted Protein Degradation Gentilly <a href="/SanofiFR/">Sanofi en France</a>  (Paris) with a fantastic program. You can click under the following link sct-asso.fr/tpdmeeting
Julien Lefranc (@lefrancju) 's Twitter Profile Photo

I keep being amazed by the work from Revolution Medicine Here is a example from their last patent. This work is again pushing medicinal chemistry out of out comfort zone. 6 chiral centers, 1 atropisomer , a spiro and an aziridine ! Congratulations to Les Burnett and all the Team!

I keep being amazed by the work from <a href="/Rev_Medicine/">Revolution Medicine</a> Here is a example from their last patent. This work is again pushing medicinal chemistry out of out comfort zone. 6 chiral centers, 1 atropisomer , a spiro  and an aziridine ! Congratulations to <a href="/Les_Burnett/">Les Burnett</a>  and all the Team!
Angewandte Chemie (@angew_chem) 's Twitter Profile Photo

If he could have dinner with a well-known historic figure, who would Alessandro Bismuto invite? @bismutolab @unibonn Find out on his #IntroducingAngewandte page x.com/16467437/statu… onlinelibrary.wiley.com/doi/10.1002/an…

If he could have dinner with a well-known historic figure, who would <a href="/AlexBismuto/">Alessandro Bismuto</a> invite? @bismutolab @unibonn Find out on his #IntroducingAngewandte page x.com/16467437/statu… onlinelibrary.wiley.com/doi/10.1002/an…
ROMERO Eugénie (@eromerohte) 's Twitter Profile Photo

Événement : journée thématique de la #chimie accélérée et digitalisée en R&D le 19 septembre prochain à Paris Saclay! Au programme Laurence Grimaud (ENS Paris-Saclay ) Pascal Mieville (EPFL), Raphaël Steimbach (Servier), Florian Médina (Johnson & Johnson) et bien d’autres !

Événement : journée thématique de la #chimie accélérée et digitalisée en R&amp;D le 19 septembre prochain à Paris Saclay!  Au programme Laurence Grimaud (<a href="/ENS_ParisSaclay/">ENS Paris-Saclay</a> ) Pascal Mieville (<a href="/EPFL/">EPFL</a>), Raphaël Steimbach (<a href="/Servier/">Servier</a>), Florian Médina (<a href="/JNJNews/">Johnson & Johnson</a>) et bien d’autres !
drug hunter (@drughunter_com) 's Twitter Profile Photo

BMS-986365: A Next-Generation Oral AR Heterobifunctional Degrader for Drug-Resistant Prostate Cancer This full case study details how BMS-986365 was engineered to have low intrinsic agonism and exert direct antagonism of WT AR and more! Full Article: drughunters.com/4dIhx9d

BMS-986365: A Next-Generation Oral AR Heterobifunctional Degrader for Drug-Resistant Prostate Cancer

This full case study details how BMS-986365 was engineered to have low intrinsic agonism and exert direct antagonism of WT AR and more! 

Full Article: drughunters.com/4dIhx9d
drug hunter (@drughunter_com) 's Twitter Profile Photo

Molecule One-Pager: ARV-471 (vepdegestrant) This molecule one-pager includes links to key presentations, publications, patents, preclinical and clinical PK data summaries, and more. One-pager link: drughunters.com/3YoQR8v

Molecule One-Pager: ARV-471 (vepdegestrant)

This molecule one-pager includes links to key presentations, publications, patents, preclinical and clinical PK data summaries, and more.

One-pager link: drughunters.com/3YoQR8v
AACR (@aacr) 's Twitter Profile Photo

The three-part New Drugs on the Horizon Series at the AACR Annual Meeting 2025 wrapped up this morning. A total of 12 first-time disclosures were presented. #AACR25

The three-part New Drugs on the Horizon Series at the AACR Annual Meeting 2025 wrapped up this morning. A total of 12 first-time disclosures were presented. #AACR25