Lei Li (@leili_bioinfo) 's Twitter Profile
Lei Li

@leili_bioinfo

PI, Computational and Disease Genomics, Bioinformatics, Genetic diseases, Single Cell

ID: 42355739

linkhttps://scholar.google.com/citations?user=PkeuDkwAAAAJ&hl=en calendar_today25-05-2009 05:19:42

1,1K Tweet

647 Followers

699 Following

brent richards (@brentrichards19) 's Twitter Profile Photo

Exciting Parkinson's disease GWAS in NG. While eQTL MR can sometimes be helpful, eQTLs from GTEx are not enriched for disease heritability. If the eQTLs don't harbour heritable signals, what do the MR results mean? nature.com/articles/s4158…

Tugce Aktas (@_taktas_) 's Twitter Profile Photo

Proudly presenting our new findings on how #RNA binding proteins (RBPs) may increase the tolerance of genomes to transposable element (TE) insertions. If you want to know more read this thread or our story nature nature.com/articles/s4158…

Alex Bick (@alexbickmdphd) 's Twitter Profile Photo

Excited to share AllofUsResearch program’s flagship genomics paper describing 245,388 clinical-grade genome sequences encompassing >1 billion genetic variants published today in nature nature.com/articles/s4158…

Excited to share <a href="/AllofUsResearch/">AllofUsResearch</a> program’s flagship genomics paper describing 245,388 clinical-grade genome sequences encompassing &gt;1 billion genetic variants published today in <a href="/Nature/">nature</a> 
nature.com/articles/s4158…
Lappalainen Lab (@tuuliel_lab) 's Twitter Profile Photo

Excited to share our review paper in Cell! With Sasha Gusev Sohini Ramachandran Yang I Li we discuss the genetic and molecular architecture of human traits, future opportunities and challenges and ways forward. authors.elsevier.com/a/1igrbL7PXqPfU

Nature Communications (@naturecomms) 's Twitter Profile Photo

Come work with us at Nature Communications! We are hiring an Associate or Senior Editor in the field of Economics, Climate, and the Environment. Apply by 15th of March. careers.springernature.com/job/New-York-A…

X.D. Zou (@bioinfor_zou) 's Twitter Profile Photo

Excited to share a new paper describing a new regulator the E3 ligase RBBP6 as an essential factor for GSC maintenance. Wenyan Chen Lei Li nature.com/articles/s4142…

Wenyan Chen (@chenwenyan5) 's Twitter Profile Photo

Our innovative approach revealed how RBBP6 orchestrates a cascade effect, ultimately reducing MYC expression—a critical factor in GSC survival. This pioneering strategy offers a promising therapeutic paradigm for glioblastoma, delivering hope for more effective treatment options

Walid Khaled (@wtklab) 's Twitter Profile Photo

I am pleased to share the final version of our Human Breast Cell Atlas with MarioniLab now out Nature Genetics. There are important new additions, which I will leave to Sara Pensa and Austin Reed to mention👇 . Couple of points i want to highlight 👇: nature.com/articles/s4158…

mireya plass (she/her) (@miriplass) 's Twitter Profile Photo

Happy to participate in the project led by @huichen1738514 and Lei Li showing the importance of alternative polyadenylation for the identification of cancer driver genes

Hagen Tilgner / @hagentilgner@genomic.social (@hagentilgner) 's Twitter Profile Photo

Our #BICCN paper is out at Nature Neuroscience Led by Anoushka+Wen Hu. Single-cell isoforms across brain regions,development&species. nature.com/articles/s4159… #LongRead #RNA iRNA_COSI #nanopore #pacbio #genomics #Transcripomics #RNAseq #Splicing Thank you Elisa Floriddia !

Xin Jin, PhD (@xinjin) 's Twitter Profile Photo

📢 Our latest paper is out in Cell! Led by the multi-talented Xinhe Zheng, we accelerated AAV-based gene delivery to 2 days & enabled in vivo CRISPR screens with single cell-level readout, a leap from existing capabilities 🤯 How does it work? (1/8)

📢 Our latest paper is out in <a href="/CellCellPress/">Cell</a>! Led by the multi-talented <a href="/XinheZheng/">Xinhe Zheng</a>, we accelerated AAV-based gene delivery to 2 days &amp; enabled in vivo CRISPR screens with single cell-level readout, a leap from existing capabilities 🤯 How does it work? (1/8)
AnaConesa (@anaconesa) 's Twitter Profile Photo

I´m thrilled to see our #LRGASP paper published in Nature Methods today. This is the work of many to benchmark long-read methods for transcriptomics, and a must-read paper for those using lrRNA-seq. Special thnks to Francisco Pardo-Palacios and Brooks Lab (1/6) rdcu.be/dJ9ev

I´m thrilled to see our #LRGASP paper published in <a href="/naturemethods/">Nature Methods</a> today. This is the work of many to benchmark long-read methods for transcriptomics, and a must-read paper for those using lrRNA-seq. Special thnks to <a href="/FJPardoPalacios/">Francisco Pardo-Palacios</a> and <a href="/TheBrooksLab/">Brooks Lab</a> (1/6)
rdcu.be/dJ9ev
Lei Li (@leili_bioinfo) 's Twitter Profile Photo

Excited to share our new paper in Science Advances . We developed a new computational method and identified widespread dysregulation of tandem transcription initiation in human cancer, many of which are independent of gene expression. science.org/doi/10.1126/sc…

Jian Yang (@jyang1981) 's Twitter Profile Photo

SMR Portal: an online analysis, visualisation, and database platform for mapping complex disease genes. Powered by Westlake FutureGene. Try it out at: yanglab.westlake.edu.cn/software/smr_p…. See a tutorial video at: yanglab.westlake.edu.cn/software/smr_p…

SMR Portal: an online analysis, visualisation, and database platform for mapping complex disease genes. Powered by Westlake FutureGene. Try it out at: yanglab.westlake.edu.cn/software/smr_p…. See a tutorial video at: yanglab.westlake.edu.cn/software/smr_p…
X.D. Zou (@bioinfor_zou) 's Twitter Profile Photo

Thrilled to share our new paper in Nature Communications! 🎉 We present an APA-enhanced framework identifying rare variants driving disease risk, distinct from expression/splicing. Rare & common variants converge in impacting disease risk. nature.com/articles/s4146…