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Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution, advancing spatially resolved multi-omics mapping. nature.com/articles/s4159…

We’re so proud of our incredible undergrads presenting at the 27th UW–Madison Annual Undergraduate Symposium today 🥳🥳 Sofia rocked her oral talk, and Krosta and Michael crushed it with their posters 🤓🤓Amazing work y'all! You make us proud 🎉🎉

The last Analytical Seminar of the spring semester was presented by Professor Francisco Fernandez-Lima from the Florida International University, showcasing the power and wide range applications of trapped ion mobility MS technology. Great science and fun interactions!

Big news in ACS Analytical Chemistry Journals 🥳🥳 A novel ultralow-flow-rate DESI-MSI platform enables subcellular spatial resolution for in situ biomolecule mapping of single cells. No complex hardware or extensive sample prep needed‼️ Congrats leo_hua_zhang and all coauthors 🎉🎉 pubs.acs.org/doi/full/10.10…

Check out our recent review on neuropeptide homology across animal phyla, now featured on the cover of ACSChemNeurosci special issue 🥳🥳🥳 Special thanks to UW–Madison School of Pharmacy Sally Griffith-Oh for creating this stunning cover art 🎉🦞🦀 ACS Publications #MyACSCover

Big congrats to our amazing lab members Shuling, Lauren Fields, Wenxin, and undergrad Sophia (a double award winner!!) for their outstanding recognition at the UW-Madison Chemistry Awards Ceremony 2025 🥳🥳 Very well-deserved for all of their hard work🎉🎉

Huge congrats to UW–Madison #ClassOf2025 🎉🎉🎉 We're so proud to watch our amazing lab members walk the stage. Cheers to Drs. Lauren Fields, Hannah Miles, Zexin Zhu, Malik Ebbini, Olga Riusech, and Zicong Wang for your hard work, big dreams, and bright futures ahead! 🍻🍻🎓🎓🍾🍾

New paper on #IJMS 🥳🥳 Using ion mobility and MS, we tracked and identified key oxidation sites that are critical for glucagon assembly from monomers to fibrils 🤓 Congrats to Gaoyuan Lu on this nice collaboration with the UT Knoxville Do lab 🎉🎉 sciencedirect.com/science/articl…

#ASMS2025 is around the corner and we can't wait to share our latest MS research with you 🥳🥳🥳 Check out the special presentation of our PI Lingjun Li at the The PEAKS Team User Meeting, 4 exciting orals and 22 informative posters from our lab this year 🤓🤓🤓

A warmhearted congrats to Li Lab 67th and 68th PhDs, Dr. Malik Ebbini and Dr. Olga Riusech 🥳🥳🥳 Your kindness and smile will be missed! Best wishes to your future endeavors 🍾🍾🍰🍰

#ASMS2025 🥳 We're ready 🔥🔥🔥 Madison ✈️✈️✈️ Baltimore, MD!

Happy Li Lab Dinner Reunion😍#ASMS2025 allows us to have a delicious meal at a local restaurant. We're all fueled to learn and share cool science over the next few days. Also, kudos to our PI Lingjun Li for delivering a fantastic talk at the The PEAKS Team User Meeting 🥳

Join us on the first day at #ASMS2025! Dr. Wei (Wilson) Li will be presenting an exciting oral on a novel chemoproteomic platform for reliable citrullination mapping in Alzheimer’s disease 🤓 Plus, don’t miss out 5 posters covering proteomics, MS Imaging, and ion mobility 🎉

Good morning #ASMS2025! Today Shuling presents on characterizing ganglioside isomers via high-res ion mobility-MS/MS, and Feixuan on high-throughput quantification of O-glycosylation in diabetes 🥳 Plus, 4 posters in multiomics, DIA, TEMI, and glycopeptide enrichment 🤓

A busy Day 3 at #ASMS2025 for the Li lab! We’ve got 10 posters covering a wide range of exciting topics. Stop by, check them out, and feel free to ask us any questions 🤓🤓

Wrapping up #ASMS2025 strong! Ángel Ibarra will be presenting an oral on sialic acid isomer characterization using permethylation & ion mobility-MS/MS 🥳 Don't forget to check out our 3 last posters on crustacean metabolomics and proteomics, and carboxylate enantiomer analysis

#ASMS2025 was a wonderful #TeamMassSpec experience. Our session chaired by Lingjun Li Research Group was awesome with great talks. Having the shuttle buses arranged was an incredibly thoughtful touch. My personal version of Faces of MS this year:

Li Lab had a great time at #ASMS2025 in Baltimore, MD ☀️🌊🐟🦀🦞 22 posters, 4 orals, 2 awards, and a plenary talk by our PI Lingjun Li 🤓 A fun Li Lab Reunion Dinner, closing event at the National Aquarium, and IonOpticks cruise trip with great views, drink, and DJ set 🛥️⚓️

Warmest congratulations to Dr. Hannah Miles Hannah Miles, the 69th Ph.D. from the Li Lab 🥳🥳🥳Your support for fellow lab members, triathlon training inspiration, and fruitful collabs with Ricke Lab have truly left a lasting impact. Wishing you the best on your next adventure 🍾🍰

Why is cocaine so addictive? A new study from Professor Lingjun Li (Lingjun Li Research Group) reveals that it’s not just about dopamine — neuropeptides across the brain play a key role. These insights could lead to better addiction treatments. Learn how: pharmacy.wisc.edu/2025/03/22/unl…