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A great collaboration with Lijuan Feng from Rockefeller University. It is a long but excited journey to explore the finding. Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation biorxiv.org/content/10.110…

On Mondays we unintentionally match 😂 can you tell we spend a lot of time together? Love this group #SozenLab #DevelopmentalBiologists Yale Department of Genetics 🔬

Last night, we were proud to unveil and install the new #bust of Dr. Yan Fuqing, Class of 1909, in the #MedicalHistoricalLibrary. Dr. Yan was the first #Asian to receive a #doctorate of #medicine from Yale School of Medicine.

Phenomenal podcast on the use of stem cell-based embryo models in The Economist interviewing my brilliant Ph.D. mentor Berna Sozen and bioethicist Kirstin Matthews out now! Listen here: economist.com/podcasts/2023/… Yale Department of Genetics Yale School of Medicine Yale University

Stoked to share a new teamstembryo preprint MPI-CBG Dresden Physics of Life Dresden📢. What drives phenotypic variation in embryo models? We discovered an important role for metabolism! tinyurl.com/43e6x7su Highly relevant: tinyurl.com/576pzzy2 Trivedi Lab Miki Ebisuya Let 's eXplain (1/17)

In ‘How to build a virtual embryo’ for Method of the Year 2023, Vivien Marx🐘📬⛅️ asks Berna Sozen Monique Pedroza Yale University Nicolas Rivron, Turlier lab, Shantanu Singh Broad Institute and others about computational ways to study early development. #moty2023 nature.com/articles/s4159…

Nature Methods' Method of the Year 2023 is methods for modeling development! For all #MOTY2023 content plus Methods to Watch, please see the Collection here: nature.com/collections/ej… We thank Berna Sozen and Magdalena Zernicka-Goetz for the beautiful cover image of mouse blastocysts!

I am delighted to share our paper “Modeling Post-Implantation Human Development to Yolk Sac Blood Emergence,” published nature – our model a.k.a. heX-Embryoids nature.com/articles/s4158…

Transitions in development – an interview with Berna Sozen In this interview, Berna Sozen talks about her journey to becoming a group leader and the importance of making science careers accessible: journals.biologists.com/dev/article/15…

SAVE THE DATE! Friday 4/19/24 Genetics Seminar Speaker Dr. Wie Xie, PhD, Tsinghua University, will present "Decoding the transcription circuitry when life begins." Link below... medicine.yale.edu/event/gensem04… All Yale School of Medicine Affiliates welcome...

Excited to share my first author postdoc paper in Developmental Cell cell.com/developmental-…

“My focus will be on people and scrutinizing processes so that they better support the diversity of needs of our members across identities including geographies and career stages." valentina greco Yale School of Medicine Yale Department of Genetics ow.ly/CbjF50SFmvL

So excited and proud that the idea of converting Erk-KTR ESCs to live embryos to visualize the link glycolysis with Erk signaling ex vivo comes true

nature.com/articles/s4158… We’re incredibly excited to present our work investigating the role of metabolism in mammalian development, out now in nature showing two state-specific spatiotemporal waves of glucose activity guiding mouse gastrulation

A brief history of metabolic gradient theory go.nature.com/3UddB8W #JournalClub by Berna Sozen Yale University

YSM researchers report previously unknown functions of #glucose, the simple sugar molecule that powers the body’s cells. In a recent nature study, a team led by Yale Department of Genetics’ Berna Sozen says glucose #metabolism helps to guide #embryonic development: brnw.ch/21wNXQw

Join us this Thursday! 👇🏻🗓️

The #ISSCR2025 program covers global breadth of stem cell research and regenerative medicine with 70% of the invited speakers as first-time ISSCR speakers. Grateful to the program committee, co-chairs Eugenia Piddini and Kathy Cheah and the ISSCR team isscr2025.org

a real pleasure to write this piece with Martin Pera and Patrick Tam, where we reflect on recent insights and open questions in early human development: doi.org/10.1242/dev.20…

In this Review, Berna Sozen , Patrick Tam and Martin Pera summarize how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questions: doi.org/10.1242/dev.20…