Honoured 🙏 to speak on mRNA lung cancer vaccine at our UCLH Annual Members Meeting. Reflecting on 30 yrs of clinical trials conducted and led here, transforming NSCLC treatment from hopelessness to hope with chemo, TKIs, IOs and possibly mRNA vaccines!

Sequencing data is key to enabling precision oncology research and implementation. A new study published by researchers at BC Cancer, @BCCancer_GSC and University of British Columbia shows that long-read sequencing is a valuable addition to the toolkit.

Fascinating how mosaicism in our tissues can influence cancer development

The rampant air pollution arising from fossil fuels has enormous costs. (99% of the world's children breathe unsafe air. WHO!) And the 7 million deaths caused by air pollution costs the world economy nearly 5 TRILLION dollars each year. (18)

This #LungCancerAwarenessMonth our message is simple - anyone can get #LungCancer - #AllYouNeedIsLungs 🫁 Misunderstandings delay diagnoses, leading to poorer outcomes. Visit allyouneedislungs.org.uk to read real stories. A joint initiative by UKALK+, @EGFRUK & Ruth Strauss Foundation.

#DRDK2024 From the first sequenced genome to cutting-edge single-cell sequencing technologies, genomics has revolutionized how we diagnose and treat cancer. A remarkable evolution transforming science into lifesaving precision medicine. #Genomics #CancerResearch GenomeBC

A new study from Dr. Marco Marra ‘s lab identifies a potential treatment strategy for cancer patients with KMT2D gene mutations, while offering a technique to find other mutation-specific treatment options in the future. Read the paper in Genome Medicine: doi.org/10.1186/s13073…

🚨So proud to present the first study from our Computational Cancer Genomics (CCG) Research Group group together with Charles Swanton Nnennaya Kanu and led by Olivia Lucas with key collaboration Sophie Ward and fundamental support Rija Zaidi Abi Bunkum & many others Out in Nature Genetics 👇 doi.org/10.1038/s41588… 🧵👇

Congratulations to Dr. Marco Marra, #TerryFox Leader in Cancer Genome Science! Dr. Marra joins 87 other appointees, including Canadian actor and Terry Fox supporter Ryan Reynolds and former Terry Fox-funded researcher Dr. Nada Jabado. 🔗 tfri.ca/updates/news/n… Marco Marra

Terry Fox started a marathon against cancer but couldn’t finish it. Others have been running in his honour since 1981. His battle was with cancer but his legacy is bringing people together. Terry Fox Foundation

I am grateful to Terry Fox Research Institute for this prestigious award! They have supported me since I was a PhD student, through trainee awards and career development opportunities at their annual meetings. I am looking forward to continue doing great science with this wonderful team!

While progress has been made in treating #NSCLC, patients would further benefit from earlier detection & interception. Here, Spira & colleagues explore advances in identifying premalignant lesions, & devise approaches for stratification + interventions. bit.ly/4brKS7N

🔥New #review out! We explore how experimental models and high-throughput sequencing (or, all the ✨#omics✨) complement each other in #metastasis research. Bridging these approaches can unlock deeper insights into #cancer progression and #treatment

🚨Thrilled to share our latest work: “Tumor-Infiltrating Clonal Hematopoiesis” NEJM - we investigated how age-related blood mutations impact cancer when they infiltrate tumors, with Elsa Bernard Maria Zagorulya, Elli Papaemmanuil, PhD Charles Swanton + more nejm.org/doi/full/10.10…

Calling all PhD graduates! We are seeking outstanding post-doctoral researchers to join our vibrant ELCHA team! If you are excited about applying 'omics technologies to study healthy aging or age-related diseases like cancer, please reach out to us!

📣Don’t miss a great opportunity to work with the incredibly talented and generous Will Hill ! Congrats Will! You and your team are going to be awesome! 💪🏻

Brilliant piece on lung cancer in people who have never smoked. bbc.com/future/article…

A new genome-wide #CRISPR screen identifies BACE1 as a driver of lung cancer #metastasis to the brain, suggesting that BACE1 inhibitors could be repurposed to prevent brain metastasis in #NSCLC. Sheila Singh Brain Tumour Lab McMaster Surgery scim.ag/4eyJwtG