
Linda O' Keeffe
@lindam_okeeffe
MRC Research Fellow @ MRC_IEU
ID: 1219434240
http://www.bristol.ac.uk/integrative-epidemiology/research/ 25-02-2013 17:58:41
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Body fat influences CVD, but it’s hard to modify. What if we focus more on muscle? How might benefits compare? Some surprising new findings: medrxiv.org/content/10.110… Thanks to Elizabeth Blackwell Institute Children of the 90s george davey smith Linda O' Keeffe Kaitlin Hazel Wade (she/her) Michael V Holmes (he/him) Nicholas Timpson Emma Vincent


REMINDER: Closing date for 2 Postdocs, 1 PhD and 1 MSc by Research with Andrew Simpkin and I is fast approaching. Get your applications in by noon on the 30th Sept!


Our paper on puberty timing and adiposity trajectoires in the Children of the 90s now available at doi.org/10.1093/humrep… @abifraser1 @laurahowe_epi Joshua Bell

Preprint of our new paper on sex-specific assocations of adiposity with 148 metabolic traits at different life stages in Children of the 90s now available at medrxiv.org/content/10.110… Prof Trish Kearney george davey smith @saepeters Kate O'Neill Matthew Lee Joshua Bell


@abifraser1 University of Bristol @laurahowe_epi @DeborahLawlor2 NIHR Bristol Biomedical Research Centre (BRC) george davey smith

Just out! We used a life course metabolomics approach to see what underpins higher CVD rates in men. This covers 4 life stages across 2 generations of Children of the 90s, including puberty & menopause transitions. All in all: I’d keep a close eye on those rising VLDLs (& shrinking LDLs?)

Many thanks to Children of the 90s Linda O' Keeffe george davey smith @DeborahLawlor2 @abifraser1 @laurahowe_epi Ana Goncalves Soares & others in MRC IEU Elizabeth Blackwell Institute. This also shows the value of repeat NMR measures from Nightingale Health. And how ‘simple’ research questions are anything but!

Well done Lisa and the rest of the Cork, London & Bristol team! Gillian Maher @abifraser1 @laurahowe_epi Chloe Park 💙 @mccarthyfergus Prof Trish Kearney

Have we been underestimating the metabolic harms of abdominal fat? Pleased to share our findings based on new UK Biobank NMR metabolic data: medrxiv.org/content/10.110… A 5-fold increase in sample size over previous studies, & a few surprises!

Detailed metabolic data finally exist at large scale. And soon to be 500k! Lots to discover. Many thanks to UK Biobank Nightingale Health, & george davey smith Michael V Holmes (he/him) @PeterWyrtz Tom Richardson Qin Wang Eleanor Sanderson Venexia Walker Linda O' Keeffe Nicholas Timpson MRC IEU Happy scrolling.

No ifs, No buts, No maybes. Green minister Malcolm Noonan MUST ensure there is funding for Biodiversity Officers in Carlow& Kilkenny. We are in the middle of a Biodiversity Crisis! Tax the 100 corporations responsible for 71% of emissions to fund a #JustTransition #ClimateChange



Does adiposity have different associations with cardiometabolic risk in females and males across the life course? See our new HealthResearchBoard funded work on Children of the 90s with Joshua Bell Kate O'Neill @saepeters Matthew Lee george davey smith Prof Trish Kearney tinyurl.com/5n8v5f7d
