🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Check out our preprint using imaging-omics to characterize the #OrganelleSignature - the morphology interactions & distribution of #ER❤️ #Lysosomes🩵 #Mitochondria💚 #Peroxisomes🧡 #Golgi💛 & #LipidDroplets🩷 - of live #neurons and #astrocytes! doi.org/10.1101/2024.1… 🧵1/11

In this episode we talked with Carl Wu from John's Hopkins University about his work on nucleosome remodeling, histone variants, and the role of single-molecule imaging in gene regulation. #podcast #epigenetics Listen here: activemotif.com/podcasts-carl-…

GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing | bioRxiv biorxiv.org/content/10.110…

I have written a concise review on chromatin transcription as part of the Journal of Molecular Biology special issue on transcription elongation. Check it out! authors.elsevier.com/sd/article/S00…

Our new paper on epigenome editing is out! We mapped which effector domains regulate transcription across genomic, cell type and DNA-binding domain contexts. Then we built new gene repressor and activator tools with improved efficiency & deliverability nature.com/articles/s4158…

Out in Nature Communications ! ChromaFold predicts 3D contact maps using single-cell ATAC-seq alone. nature.com/articles/s4146…

Agreed! That's why I wrote ggpubfigs, a ggplot2 extension that *only colorblind-friendly color palettes. Easily make your figures colorblind-friendly with ggpubfigs! x.com/NKWhiteman/sta…

📢 New preprint alert: We’ve just published a deep dive into the role of tandem repeats (#TRs) in single-cell gene expression across the immune system, using #WGS and #scRNA-seq data from 1,790 individuals and over 5 million blood cells! 🧬 🧵👇 #repeats #SingleCell 1/9

Greatly looking forward attending #ASHG24 Look forward seeing cool science and old friends. Bjornsson lab is thrilled to have three amazing stories to share this year. #ASHG2024 #ASHG24

New in JBC press: "Scientists' findings demonstrate altered microglial states and metabolic disruption following Aβ deposition." Learn more: jbc.org/article/S0021-…

Jeremy Herskowitz, Ph.D., is a corresponding author on a study published in Nature Neuroscience that identifies hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the brain. UAB Heersink School of Medicine buff.ly/3C9w9AT

Excited to share our preprint, describing a method for heritability partitioning with GWAS sumstats that significantly improves upon S-LDSC Led by the fantastic Hui Li, and co-supervised by Xihong Lin #ASHG24 poster 4089F medrxiv.org/content/10.110…

Only the 1st installment with much more to come…the 1st ReDLat Genomics Report 🧬 highlights ancestral background and pathogenic variation! Full-sized ms w/local ancestry mapping, pedigrees, + detailed clinical vignettes will be in published paper! medrxiv.org/content/10.110…

I’m thrilled to share one of the largest single-cell transcriptomic atlas of the human DLPFC with over 6.3M nuclei from 1,494 unique brain donors. Collaboration with Mikaela Koutrouli Nick Gabriel Hoffman Jaroslav Bendl John Panos Roussos and #PsychAD Consortium doi.org/10.1101/2024.1…

Excited to share our latest preprint, as part of ENCODE4, on a consensus variant-to-function (cV2F) score for functionally prioritizing variants for complex disease - led by Tabassum Fabiha and co-mentored with Alkes Price. biorxiv.org/content/10.110…

Joao Pereira, Ph.D., joined our faculty as an assistant professor in July 2024. Read about his passion for neurodegenerative diseases and excitement for his new role in the department: buff.ly/40VPbFr UAB Heersink School of Medicine

Register for the Tri-Institutional Future Scholar Symposium: Genetics and Cancer! Hear experts, meet with postdoctoral researchers and network with fellow senior graduate students and postdoctoral fellows. Register at tinyurl.com/4nm6bewa @VUMC_Cancer UNC Lineberger

The registration deadline has just been extended to Feb 27th!

I am not normally an alarmist, but these are not normal times. This change would cripple research infrastructure at hundreds of US institutions, and threatens to end our global superiority in scientific research. grants.nih.gov/grants/guide/n…