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2023 Small Molecule Approvals! @drughuntersite A lot of fascinating firsts in 2023 including: -The first FDA-approved oral ER degrader -The first FDA-approved reversible BTK inhibitor -The first FDA-approved gamma-secretase inhibitor (not in Alzheimer’s!) -A reversible

The EMBO practical course on NMR spectroscopy will be held in Grenoble this year. If you are interested, you can sign up here to be informed when the course is open for applications: coming-soon.embo.org/pc24-35

Ok in honour of #jungleimafraid, the absolute heroes at BBC Radio 6 Music have released my #Cloudbusting mix for this coming Friday’s show with the legend that is Lauren Laverne First one goes out to all original junglists Happy Saturday night BBC Sounds bbc.co.uk/sounds/play/m0…

George Carter is a 3rd year Microbiology student in @LivUniLifeSci - read about his experiences on a lab placement UC San Francisco in our latest blog: bit.ly/3tJYpqd #research

Great opportunity to present your latest research into Mechanisms and Consequences of Redox Signaling at grc.org/thiol-based-re… -many talks to be selected from abstracts but program already very exciting. grc.org/thiol-based-re… too if you are an early career researcher.

Fantastic to see this work from Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology on the front cover of J Cell Science. Congratulations to everyone!

Latest from our conformational ensemble prediction pipeline with modified AlphaFold2: This is NOT a trajectory from MD! It took two hours to predict this conformational ensemble using one GPU. The experimentally-resolved energy barrier for this transition is > 15 kcal/mol

The more we learn about patient-specific PKA signaling in disease, the more interesting it gets. Great UK/US collaboration published today Science Advances Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs science.org/doi/10.1126/sc…

🎉 Abstract submissions are open for our new annual #BiochemSocFest! Let's celebrate the scientific disciplines and activities that define the Biochemical Society's work. Submit your abstract to one of our 8 research areas before 9 May: ow.ly/BKyA50QrjJB

A big Liverpool welcome to Dr Kirsty McMillan Biochemistry, Cell and Systems Biology to give today's Inst of Systems, Molecular & Integrative Biology seminar. We can't wait for Kirsty to start as a Tenure Track Fellow at University of Liverpool later this year!

Check out work from our department as well as Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology ZechLab Eleanor Hargreaves bxv_biochem

Sulantrix Ltd are delighted to be sponsoring the 2024 EMBO workshop on pseudoenzymes in Spain, June 10th-13th 2024 meetings.embo.org/event/24-pseud… organised by James Murphy ergiola Zeqiraj Hayley Sharpe EMBO

Important from Urszula McClurg 🇺🇦 Inst of Systems, Molecular & Integrative Biology. Agree totally: 'By improving accessibility, we not only enhance the conference experience for all, but also inspire a new generation of scientists who can envision success in an inclusive profession'. doi.org/10.1038/s41556…

Pyrophosphorylation is extensive in human proteins. (phosphorylation of pSer to ppSer) nature.com/articles/s4158…

New review of evidence for protein diffusion in extracellular matrix, involving sliding, chain switching and rolling interactions of proteins with heparan sulfate led by @DaveFernig Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology portlandpress.com/essaysbiochem/…

Happy to host any applicants that are interested in low oxygen sensing and response at all levels. Also crosstalk with inflammation response! Biochemistry, Cell and Systems Biology Inst of Systems, Molecular & Integrative Biology

A fantastic trip to UGA for the University of Liverpool Inst of Systems, Molecular & Integrative Biology Faculty of Health and Life Sciences team. After 10 years, the Liverpool partnership with UGA is poised for further exciting developments. Thanks for your amazing hospitality!

Faculty of Health and Life Sciences Biochemistry, Cell and Systems Biology Health and Life Sciences Public Engagement

A comprehensive review into current understanding of ubiquitin and ubiquitin-like proteases (ULPs), including their mechanisms and relevance to human diseases. doi.org/10.1042/BCJ202…

Inst of Systems, Molecular & Integrative Biology Molecular & Clinical Cancer Medicine (MCCM) Biochemistry, Cell and Systems Biology Photos of fantastic University of Liverpool scientists sharing their ground breaking research with the MAVS visitors Sarah Barnett Adam Albanese and Dr Jan Schulze. Thanks to Professor Judy Coulson for hosting.