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When I was in elementary school, my mom started going blind. Retinitis pigmentosa. No family history. No treatments. No cure. I got lucky. She didn’t. It led me to build Orchid so my baby —and everyone else's—gets to win the genetic lottery—avoid blindness— and hundreds of

The first pivotal, FDA-enabling clinical trial of a longevity drug is now fully enrolled We will monitor these dogs for the next ~4 years, quantifying millions of data points across biological changes, quality of life, disease, + lifespan

I've always disliked the 'societal decision' that medicine must only address things that are wrong rather than also making life better for those who are supposedly healthy - after all, who is to judge what 'healthy' really means?

It seems like ChatGPT would be a lot more powerful if it had reasonably good visual capabilities. As far as I know, it doesn't have such abilities - does anyone know why computer vision seems to have lagged behind text here? (There's plenty of image data to train on?)

Astronomical clock in Venice

stoicism is overrated; listening to passion, inspiration and emotion is still HIGHLY underrated.

Promising strategy for accelerating translational lipid nanoparticle research by screening pooled barcoded batches in terminally ill nonhuman primates (NHPs). This minimizes the NHPs needed for experiments and avoids harming healthy NHPs. nature.com/articles/s4158…

Deep dive by Abhishaike Mahajan ("Owl Posting") into Nabla Bio's unique computational strategy for engineering soluble versions of transmembrane proteins to facilitate more efficacious antibody screening. Very interesting exploration here! owlposting.com/p/better-antib…

A very interesting glimpse into how policymakers use a very different approach for learning about science than us scientists tend to expect. Keeping this in mind may help us better communicate science in policy settings, moving us towards better policies. issues.org/information-fl…