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Here’s a fun one. Poop out after 18 months in low tau subset?

Always worth listening to what Lon S. Schneider, MD has to say about the interpretation of clinical trial data.

@ResearchGate wrongly emailed out a retraction of our The Lancet paper. They have retracted the retraction badge but say they can't tell those emailed despite our reputational damage. Please tell people. Robert Howard Naaheed Mukadam Lon S. Schneider, MD thelancet.com/article/S0140-…

Gill Livingston ResearchGate The Lancet Robert Howard Naaheed Mukadam Lon S. Schneider, MD Sorry about this Gill. Have shared. Best wishes.

barttels Madhav Thambisetty Eric Widera, MD Simon Mead Andrew Lees Robert Howard Jason Cohen Shibley Lon S. Schneider, MD Seb Walsh Michael Schöll @VincentPlanche @StefanoSensi14 Alberto J Espay Nicolas Villain / Moved to LinkedIn & BlueSky @KasperKepp @PhilAlz Gill Livingston @DrTFromKC @jfballenger @jasonkarlawish James Rupert Fletcher Adam M. Brickman Dr. Jennifer Manly Sarah Ackley, PhD FORTUNE TIME Erin Prater, M.A.², CHES® TIME Financial Times Hannah Kuchler CTAD NIH Alzheimer's Association Howard Gleckman American Geriatrics Society Kathy Liu Richard Merrick Nancy Lundebjerg (she/her/hers) Nathaniel Chin U.S. FDA NICE Raymond Koopmans Maastricht University Kariem Ezzat Dr Ben Underwood NHS England Not sure what ResearchGate is upto, but they have erroneously retracted Gill Livingston et al's The Lancet paper on dementia ⬇️ x.com/Gill_Livingsto…

Gill Livingston ResearchGate The Lancet Robert Howard Naaheed Mukadam Lon S. Schneider, MD “They have retracted the retraction badge but say they can't tell those emailed despite our reputational damage.” Can’t or won’t?

Talia Isaacs Gill Livingston ResearchGate The Lancet Robert Howard Naaheed Mukadam @researchGate @RGsupport should retract their made-up retraction. least they could do. Maybe Elsevier Elsevier News The Lancet should sue.😀

Yup, we’ve always suspected that Alzheimer pathology is mainly a plumbing problem — waste management.

Gill Livingston Juando Gispert ResearchGate The Lancet Robert Howard Naaheed Mukadam Lon S. Schneider, MD Thanks for communicating this. Since we have cited this paper, I got several notifications from them. Last one was this past Friday. Had no idea the retraction badge was a mistake.

Looks like extension of phase 2 lecanemab withdrawal period and phase 3’s open label extension.

Looks like open label extension of p3 lecanemab’s low tau subset. I’m sure there’s disease modification there somewhere.

The only reason for the divergence at all was the zeroing out of the baseline with multiple covariate adjustments. As both curves started at the same value, definitionally, they had to diverge.

Sorry, this is disease modifying (if you thought the graph was of an antibody). As “everyone knows” cholinesterase inhibitors are symptomatic, then this donepezil graph must be showing a symptomatic effect. It just can’t be otherwise.

Lilly $LLY shareholders? That’s vanguard, fidelity, black rock, state street, jpm, anyone with a 401(k), pretty much all of us. I should start acting like an owner? FDA! Free donanemab! From coast to coast, ocean to ocean, river to sea?

Wow. Joe Scarborough just decimated Donald Trump, the Republican Party, and Fox News in under 3 minutes for constantly hating America. Blown away by how well said this was. Certainly worth a watch👇

Many rushed to shame Duke University for what happened today, at the Graduation ceremony - a bunch of pro-palestine students booed Jerry Seinfeld and left before his speech. I know from personal sources that Duke handled exemplary the whole anti-jewish ordeal. There were no encampments,

Tip of the iceberg. This kind of fraud tends to pay as it gets the molecule through pre- & clinical tox & into phase 2/3 trials that could easily be positive on an outcome by chance alone, or hook and crook. Anyway, Cassava will have him pardoned on January 20 if they pay up.

On Wednesday at 415p in #Philadelphia the The Lancet commission on dementia diagnosis prevention and treatment will present its 3rd report at the #AAIC24 #AAIC2024 beginning of there or be square Or you can see Arsenal play Liverpool at Lincoln Field in Philadelphia.

Paul Jerome Lamont Simon Mead Seb Walsh Ash Paul LogarithmicDis 🦋🇺🇸🇨🇦⛷️🔬🏨 Nicolas Villain / Moved to LinkedIn & BlueSky Eric Widera, MD Jason Cohen LTCShop.com @Jeff_Browndyke Lon S. Schneider, MD Robert Howard Madhav Thambisetty @KasperKepp Trey Bateman @DanielErsk1ne Shibley Alberto J Espay @PhilAlz Michael Schöll @VincentPlanche @StefanoSensi14 Gill Livingston @DrTFromKC @jfballenger @jasonkarlawish James Rupert Fletcher Adam M. Brickman Dr. Jennifer Manly Sarah Ackley, PhD Howard Gleckman Kathy Liu Richard Merrick Nancy Lundebjerg (she/her/hers) Nathaniel Chin Emmy Betz, MD, MPH 🇺🇲🩺🔬🤝❤️ Joanne Ryan Maggie Aime, BSN, RN | Freelance Writer Oskar Hansson David Jones Jenni Burton 💙💚 Storm Newton Alzforum "Gantenerumab significantly increased CSF Aβ42 compared to placebo at year 4 (Supplementary Fig. 5, P < 0.001)" nature.com/articles/s4159…

Oct 22 2024, “the totality of the data supports the potential of HGF modulation for the treatment of neurodegenerative diseases” Javier San Martin CMO Nov 7 “Athira has paused further development of fosgonimeton…and are exploring partnering options” What changed in two weeks?