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Images from yesterday evening's Student Mixer... ;-)

🚨🚨🚨 We are hiring! We are looking for 2⃣ PhD students who want to join us @StratinghInst for awesome research in the field of continuous #enzyme #evolution! Informal questions per DM. Click the link below to apply! #MolecularEvolution Please RT! rug.nl/about-ug/work-…

It's time to mark the end of an era in our old labs with a new group photo! As we say goodbye to our old building at #Nijenborgh4, we are very excited for our next chapter in the brand new #FeringaBuilding! @StratinghInst University of Groningen

Turning Boron proteins into functional enzymes was the most challenging but rewarding project of my career (so far)! I learned so much during this project and want to thank all collaborators and members of the Roelfes and Mayer group narf42 for their support!

Nature research paper: Boron catalysis in a designer enzyme go.nature.com/4bxKuDT

Boron catalysis in a designer enzyme (nature): nature.com/articles/s4158… (Roelfes Group (find us as @roelfesgroup on BS), Lars Longwitz, Reuben B. Leveson-Gower).

A newly designed enzyme containing boron shows promising catalytic properties currently not found in nature. It could lead to applications in fields such as medicine or green chemistry. In nature Led by Roelfes Group (find us as @roelfesgroup on BS) University of Groningen with Structural Biology Group ▶️esrf.fr/home/news/gene…

This month, an exciting paper has been published in nature from Roelfes Group (find us as @roelfesgroup on BS), reporting the design of a boronic acid-integrating #enzyme that allows chiral #organocatalytic reactivity not achievable with natural or chemical catalysts. 1/3

Presenting my results from the Roelfes Group (find us as @roelfesgroup on BS) at #nordbioII in Stockholm. A great event so far, lots of interesting biocatalysis.

Design and Evolution of an Artificial Friedel–Crafts Alkylation Enzyme Featuring an Organoboronic Acid Residue | Journal of the American Chemical Society Total Synthesis and Methodology Highlights #FriedelCrafts #Alkylation #Biocatalysis #Organoboronic pubs.acs.org/doi/10.1021/ja…

Hanging out at my poster P4-2 at #biocat2024. Come talk to me about not boring, but boron enzymes.

Cool paper using LmrR Boron Enzymes!

Lars Lars Longwitz presented his work on Boron catalysis in designer enzymes at #biocat2024 in Hamburg. Check out his poster P4-2 and find out more about this remarkable new mode of activation in biocatalysis.

What would a reaction like this be called? Not really a deracemization, not really a desymmetrization, a double kinetic resolution?

Another boron enzyme from my postdoc, this time with a new protein scaffold. Getting closer and closer to natural enzymes design with our own catalytic dyad! Thanks to all who contributed!

Fantastic start of 2025 for the group. Our own Lars Longwitz won the University of Groningen FSE Postdoc prize for 2024. This prize celebrates his excellence in research and great potential of becoming a scientific leader. Well well deserved Lars! 👏 @StratinghInst

A good start to the new year: I was awarded the Postdoc Prize 2024 of the Faculty of Science and Engineering in Groningen! Very happy to receive this award to recognize my achievements in the Roelfes Group (find us as @roelfesgroup on BS) ! Now, I am looking for a new adventure!

After more than 4 years abroad, I am going back to Germany to join Universität Hamburg as a lecturer of organic chemistry! I will miss Groningen immensely, but now it is time for something new!

After my first week at Universität Hamburg, I am even more excited than before. Lots of interesting chemistry, motivated students, welcoming colleagues and a super-team of supporters, especially in the IT. I can't wait to give my first lectures in "Hörsaal A" next week. 🦥

For updates of the lab and a small sneak peak of "Longwitz Lab" science, you can now visit the group's website, all about Evolvable Catalysis. chemie.uni-hamburg.de/institute/oc/a…