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The combination of nivolumab and ipilimumab in patients with metastatic colorectal cancer led to 24-month progression-free survival of 72%, as compared with 14% with chemotherapy. Read the full CheckMate 8HW trial results: nej.md/4eGp1tj

A study in Nature Cardiovascular Research maps the expression of immune checkpoints in atherosclerosis and examines the influence of lipid-lowering treatments and type 2 diabetes to understand how immune checkpoint inhibitors worsen cardiovascular risk in cancer survivors. go.nature.com/3CUR5Mt

Early but promsing data just presented by Marc S. Raab at #ASH24 on using bispecific antibodies in first line! A 100% of patients tested who received teclistamab with Dara + Len or Dara + Len + Bortezomib were MRD negative after just 3 cycles of induction! #mmsm #myeloma

EXCITED to share my PhD work in Cell. We found that the chance of developing metastasis is partly decided by the DNA we inherited. We identified a germline variant in PCSK9 present in 70% of the white women conferring higher risk of breast cancer metastasis. (1/9)

Happy to share our latest research with Dan M Roden MD Vanderbilt Health claesson koivisto rune : Polygenic Predictor of Baseline QTc is Associated With Sotalol-Induced QT Prolongation | Circulation ahajournals.org/doi/10.1161/CI…

Today The Lancet Reg Health-Europe, immune checkpoint inhibitor "myasthenia gravis syndrome" is overwhelmingly a myositis with peculiar pseudobulbar clinical features => Major impact on how to treat ! Javid Moslehi Joshua Levenson, MD Salim S. Hayek, MD Lorenz Lehmann Jarushka Naidoo sciencedirect.com/science/articl…

1. Excited to share our paper published in nature today, introducing CD45-PET as a robust approach for noninvasively imaging inflammation. rdcu.be/d688j nature.com/articles/s4158…

High-risk PCI: A clinical consensus statement Developed by EAPCI & ESC WG on Cardiovascular Surgery, this document defines procedural and technical requirements to enhance PCI safety and efficacy in patients with surgical contraindications. Giuseppe_Tarantini MIЯVΛƬ #IC #EAPCI

The NIH has reportedly advised scientists to remove references to mRNA vaccine technology from grant applications, signaling a potential shift away from this research field. As a reminder mRNA vaccine technology is one of the most groundbreaking advancements in modern medicine.

From the international ICI-myocarditis registry - Left Ventricular Systolic Dysfunction at presentation capture both past medical history ofcardiac insults and immune checkpoint myocarditis severity Javid Moslehi Han Zhu Salim S. Hayek, MD Joshua Levenson, MD @vgzm sciencedirect.com/science/articl…

Finally, we are recruiting fellows for 2026 at UCSF for #CardioOnc & Immunology! Also looking for those w/ basic and translational interest (&background)! Who wants to join this distinguished group of fellows & alumni? Email me if interested: [email protected]

Per Boston Globe, ALL Harvard Medical School grants from federal government are cancelled. Here's the pie chart of their budget. The cancellations affect everything, from biostatistics department to longevity researcher David Sinclair. Story from Boston Globe in reply.

Circulation Research May 23rd Issue is Out! Compendium on Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases In this issue read 14 reviews & 5 Research Letters: ahajrnls.org/4kaMnLo Gabriele G. Schiattarella Maria Kontaridis

Circulation Research Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases Insights into Heart-#Tumor Interactions in Heart Failure ahajrnls.org/43vQ730 Authored by Tal Caller & colleagues. JONATHAN LEOR Kathryn Moore Lab Sean M Wu, MD PhD Lorenz Lehmann

Excited to report this important collaboration which we hope helps us understand ICI-myocarditis better, published in #EHJ today! Along with the great DrJE-Salem! EHJ Editor-in-Chief Johann Bauersachs #CardioOnc UCSF Cardiology UCSF Helen Diller Family Comprehensive Cancer Ctr academic.oup.com/eurheartj/adva…

At last—our analysis predicting severe outcomes in ICI-myocarditis is out. With just ECG, LVEF, troponin, and clinical history, you can estimate risk at initial presentation. Grateful for the incredible mentorship Javid Moslehi DrJE-Salem .. true world-class investigators!

Great science, packed rooms + so nice to meet all the collaborators and friends!!! Thanks for the perfect organization 🙏🏻#ESCardioOnco2025

Proud on my research fellows!!who presented 8👀abstracts about their exiting work on preclinical models and clinical data 🦀🫀🔥🚀at 1st Cardioonco Congress of the ESC! #ESCardioOnco2025 Herzmedizin.de European Society of Cardiology