
Luke McAlary
@lukemcalary
Researcher from IHMRI and UOW trying to find out cause and cure for MND
ID: 797652912
02-09-2012 06:26:58
258 Tweet
280 Followers
578 Following

Most people with ALS lack known mutations, making early detection tough. We built an AI model using data from 47k+ people in 13 countries to spot risk, even without family history. Proud to support this with Alfredo Iacoangeli Ammar Al-Chalabi medrxiv.org/content/10.110…





New publication. We quantify the aggregation of >100,000 random protein sequences to train CANYA, a convolution-attention hybrid neural network to predict aggregation from sequence. With Benedetta Bolognesi Centre for Genomic Regulation (CRG) Wellcome Sanger Institute IBEC science.org/doi/10.1126/sc…





New cocktail 🍹 in town - in collaboration with Ben Lehner : Massive combinatorial mutagenesis + amyloid kinetics selection + thermodynamic modelling showing us the portrait 🎨 of an amyloid transition state. Read about it in this great thread by co-first author Anna Arutyunyan


Dr. Bedlack is known in the ALS community for his rockstar suits, and his non-conventional wardrobe is also a reflection of his out-of-the-box approach to finding a cure for ALS. To watch a trailer for his Stitching Strength documentary, visit alsclinic.duke.edu Duke University
