Our session on Metals in Health and Disease is happening today at 1:30! Come check it out to learn about the role and regulation iron and zinc in the vasculature, kidney, and liver! #APS2024 Subhashini Bolisetty

This session looks great! If you’re at #APS2024 come and hear about pannexins from Manuel F. Navedo Scott Earley Dr. Miranda Good, PhD Mike Koval (keynote IGJC2024) Swapnil Sonkusare 🦕Brant Isakson🦖

Amazing story by Melissa Luse (Melissa Luse) on how nitric oxide derived from loss of Cav1 during obesity regulates CD36 presence at the endothelial plasma membrane by competing with palmitoylated residues! This post translational switch is key for endothelial func/serum lipids

🚀 Exciting news! The preliminary program for the 30th Anniversary of the Nitric Oxide Gordon Research Conference drops in a week! 🎉 Stay tuned for an inspiring lineup of speakers and groundbreaking research. #NitricOxide #ScienceConference #GRC #Research 🧪🔬

The program for the 2025 Nitric Oxide GRS has been posted! grc.org/nitric-oxide-g… @heuser_k and I are looking forward to a great trainee-focused meeting!

Breaking news📣! The preliminary program for the Nitric Oxide Gordon Conference 2025 is now online! 🎊 🗓️ Feb 9-14, 2025 📍 Ventura, CA More info: grc.org/nitric-oxide-c… #NitricOxide #GordonResearchConference #Science #Medicine

Fun paper by Melissa Luse describing how direct endothelial-adipocyte cell-cell contact with gap junctions influences adipose function

Currently taking Post-Doctoral application nominations to our T32 training grant

Congrats to twitterless Skylar Loeb for rocking her Quals!

Hey! That’s my sister! Check out her master’s thesis work where she is building models to predict coastline erosion and engineering natural shorelines which mitigate damage to key ecosystems.

For those that are making the move, I’m now on 🦋 @lukedunaway.bsky.social. I’ll plan to keep both accounts active for now.

I am thrilled to announce that a preprint of my current work is up. You can find it here: assets-eu.researchsquare.com/files/rs-61491…. To state succinctly- we show that microglia localize to capillaries where they mediate capillary dilation via the enzymatic action of cyclooxygenase-1. 1/n

I will resubmit this data in my K99 application Monday. I'm hopeful for a great score. If you are coming to the Gordon Glia meeting, please come to my talk Thursday evening! Finally, I'll be applying for faculty positions later in the year.

Luke Dunaway, PhD, recently received an American Heart Association Career Development Award to study iron's role in chronic kidney disease. Luke is a postdoc in the Isakson Lab and member of our Cardiovascular Training Program. Congratulations! Read more: cvrc.virginia.edu/luke-dunaway-p…

Check out our latest paper reviewing the regulation of vascular tone! Big thanks to co authors Tré Mills Eyo 🦕Brant Isakson🦖 onlinelibrary.wiley.com/doi/full/10.11…

Headed to #APS2025! Two great talks tomorrow from the Isakson Lab in the MCS session. Wyatt Shug (8:30AM) will present on basophil-endothelial crosstalk, and Skylar Loeb (10:50AM) will present the novel identification and impact of hemoglobin-alpha in cardiac lymphatics.

To wrap up this series, this year (2025) in a soon-to-be-published study, Tré Mills is revealing that microglia (rather than BAMs) maintain basal capillary tone through vasodilatory COX1 signaling. A pre-print is available here: researchsquare.com/article/rs-614….🤩#20YearsInVivoMGImaging

Why travel to Denmark to collect samples from a giraffe's heart? 🦕Brant Isakson🦖 lab members Skylar Loeb and Luke Dunaway, PhD, made the trip to learn more about diastolic heart failure. Red more: cvrc.virginia.edu/cvrc-trainees-…