John Lukens (@lukensjohnr) 's Twitter Profile
John Lukens

@lukensjohnr

Neuroimmunologist studying MS, autism, Alzheimer's disease, and brain injury at the University of Virginia. Father of two. Fan of Philly sports and US soccer.

ID: 2790454797

linkhttps://www.lukenslab.com calendar_today29-09-2014 02:18:10

5,5K Tweet

13,13K Followers

2,2K Following

Max Lugavere (@maxlugavere) 's Twitter Profile Photo

The first trial of creatine in Alzheimer’s disease was just published and the results are big. Patients took 20 grams of creatine monohydrate daily for 8 weeks. Brain creatine levels rose 11%, and cognition significantly improved across multiple domains, including memory,

The first trial of creatine in Alzheimer’s disease was just published and the results are big.

Patients took 20 grams of creatine monohydrate daily for 8 weeks.

Brain creatine levels rose 11%, and cognition significantly improved across multiple domains, including memory,
Waggoner Lab (@labwaggoner) 's Twitter Profile Photo

Astrocyte-derived CCL5 mediates brain infiltration of CCR5+ neutrophils that drives depression progression science.org/doi/10.1126/sc… Science Advances

Astrocyte-derived CCL5 mediates brain infiltration of CCR5+ neutrophils that drives depression progression
science.org/doi/10.1126/sc…
<a href="/ScienceAdvances/">Science Advances</a>
John Lukens (@lukensjohnr) 's Twitter Profile Photo

Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to promote aging-related white matter degeneration Nature Neuroscience nature.com/articles/s4159…

Alzheimer's Assoc CWVA (@alzheimerscwva) 's Twitter Profile Photo

Investing in Alzheimer’s & dementia research, gives scientists the tools they need to better understand how to prevent, detect, diagnose, & treat dementia. Ask Congress to increase research funding at the NIH by an additional $113.485 million. bit.ly/42VytGH

Investing in Alzheimer’s &amp; dementia research, gives scientists the tools they need to better understand how to prevent, detect, diagnose, &amp; treat dementia. Ask Congress to increase research funding at the NIH by an additional $113.485 million. bit.ly/42VytGH
John Lukens (@lukensjohnr) 's Twitter Profile Photo

GADD45G operates as a pathological sensor orchestrating reactive gliosis and neurodegeneration: Neuron cell.com/neuron/fulltex…

John Lukens (@lukensjohnr) 's Twitter Profile Photo

STING deletion protects against amyloid β–induced Alzheimer's disease pathogenesis alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

John Lukens (@lukensjohnr) 's Twitter Profile Photo

Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution: Neuron cell.com/neuron/fulltex…

John Lukens (@lukensjohnr) 's Twitter Profile Photo

On this Memorial Day weekendšŸ‡ŗšŸ‡ø, I wanted to thank Dr. Edlow Brian Edlow and the research community at Harvard Harvard Medical School for helping to keep the heroes in our military safe. Larkin's War | Sunday on 60 Minutes cbsnews.com/video/larkins-… via CBS News

Si Ming Man (@simingman1) 's Twitter Profile Photo

😊Delighted to share our latest #publication in collab with Dr. Rajendra Karki & colleagues from Seoul National University. In this Nature Communications paper, we show that #acrolein, a byproduct of our cells but also found in #cigarette smoke, #kills cells & contributes to #inflammation ourANU 1/3

😊Delighted to share our latest #publication in collab with Dr. Rajendra Karki &amp; colleagues from <a href="/SeoulNatlUni/">Seoul National University</a>. In this <a href="/NatureComms/">Nature Communications</a> paper, we show that #acrolein, a byproduct of our cells but also found in #cigarette smoke, #kills cells &amp; contributes to #inflammation <a href="/ourANU/">ourANU</a> 1/3
John Lukens (@lukensjohnr) 's Twitter Profile Photo

IRF1–expressing astrocytes are epigenetically controlled and exacerbate traumatic brain injury-associated pathology in mice science.org/doi/10.1126/sc…

IRF1–expressing astrocytes  are epigenetically controlled and exacerbate traumatic brain injury-associated pathology in mice 
science.org/doi/10.1126/sc…
John Lukens (@lukensjohnr) 's Twitter Profile Photo

Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis: Immunity cell.com/immunity/fullt…

Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis: <a href="/ImmunityCP/">Immunity</a>  cell.com/immunity/fullt…
Pluchino lab - Regenerative Neuroimmunology (@pluchinolab) 's Twitter Profile Photo

The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions: Cell Reports cell.com/cell-reports/f…

John Lukens (@lukensjohnr) 's Twitter Profile Photo

PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling biorxiv.org/content/10.110…

PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling biorxiv.org/content/10.110…
Arkady Khoutorsky (@akhoutorsky) 's Twitter Profile Photo

A new study from the lab, led by Kevin Lister, in Journal of Clinical Investigation. We demonstrate the role of mRNA translation in regulating microglial reactivity and pain hypersensitivity. jci.org/articles/view/…