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UTROSCT *⃣Pattern similar to SCTs *⃣ May be at the base of adenosarcomas *⃣ ESR1 and GREB1 Fusions *⃣ Necrosis, mitoses >2/10, ESR1 with rhabdoid diff, GREB1 fusion: RECURRENCE #GynPath #GynPathQuiz Last two photos from Dr Bennett's @pathcast lecture: youtube.com/watch?time_con…

Great discussion & photos, even for those (like me) who aren't #hemepath inclined 😉 #pathtweetaward 🏆

70s F 4cm neck mass. Dx? #PathX #PathTwitter

This is a case a pseudoendocrine sarcoma, currently thought to be an intermediate-grade sarcoma with a propensity to arise in paravertebral soft tissues of older patients. Negative for NE markers. Can show patchy S100 and nuclear beta-catenin. Photos excerpted from:

70F vulvar irritation, diagnosis? A) Lichen sclerosus et atrophicus B) Lichen planus C) Differentiated VIN 🔬dpa-dapa.com/public/present… #GYNpath #PathTwitter #Pathology 🙏 Lewis Hassell

Circumferential Perineural Invasion by Prostate Cancer ~ #GUpath #Pathology

Here's a great chance to PLEX your #neuropath muscles and diagnose this neck mass in an NF2 patient. #pathology #PathTwitter

Dermatofibrosarcoma protuberans (DFSP) with a typical honeycomb appearance. This one shows entrapment of a few nerves (largest 0.3 mm), otherwise classic DFSP. Diffusely positive for CD34 (image not shown). #dermpath #PathTwitter #PathX #BSTpath

A case of matrical carcinoma, the malignant counterpart of pilomatricoma, characterized by the presence of ghost cells👻and β-catenin nuclear-membranous positivity in basaloid cells (negative in transitional and ghosts) #pathology #dermpath #dermatology #MedX #PathX #dermatologia

Proposed Risk Stratification Model for Inflammatory Myofibroblastic Tumor (IMT) It was originally thought that IMTs were benign, but this is not always the case If tumor falls in the intermediate risk, then it is recommended to do NGS -Only ALK fusion : Low risk -ALK fusions and

65♀️ w/ thigh mass Classic scenario for #bstpath, but is it... #tooFARtodiagnose? 🤔 Stay tuned, answer will be posted tomorrow (10/16)!

A stunning example of hybrid SEF/LGFMS. MUC4 = diffusely positive. Most cases harbor FUS::CREB3L2 fusions, similar to that seen in most LGFMS. #BSTpath #Sarcoma

65♀️ w/ thigh mass 💡 ANSWER ➡️ Intramuscular myxoma 🚨 Cannot reliably distinguish from low-grade MFS on biopsy 🦔 Reccomend descriptive dx in limited samples (ex. hypocellular myxoid neoplasm) WSI 🔷️ IMM: kikoxp.com/posts/50548 🔶️ MFS: kikoxp.com/posts/18776 #bstpath

Intramuscular myxoma 👩‍🦰 Adults >40 y/o 🦵 Prox limbs, thigh🥇 🐢 Slow growth 🔎 Hypocellular & hypovascular 🥷 Infiltrates muscle at periphery 🔬 Myxoid w/ fine collagen ✨️ Small bland spindle/stellate cells 🧬 GNAS mutations 🎭 Cellular variant w/ ⬆️ collagen #bstpath #kiko25

Finishing this week by contrasting a Benign Brenner with a Borderline Brenner and a Malignant Brenner Tumor, of the ovary. 🤩 #gynpath #pathx #PathTwitter #UMiamipath UMiami Pathology

History of breast cancer and radiotherapy. Flesh-colored papule. Benign or malignant? 🔬kikoxp.com/posts/3457 #BreastPath #DermPath #BSTPath #PathTwitter #Pathology

This case tricked me. Deeper levels show better preserved/less degenerated areas showing neutrophils. It's a fledgling abscess!

The International Society of Bone and Soft Tissue Pathology now has an official Twitter (X) account, International Soc of Bone & Soft Tissue Pathology. Our hope is that this site will further promote the goals of the ISBSTP: 1 ) To offer resources to bone and soft tissue professionals.

🔬Diagnosis & Annotated Pearls | Previous Case! ➤ MYXOID LIPOSARCOMA, Thigh #Pathresidents #PathTwitter #BSTpath CAPathologists #pathX #path2path PathologyOutlines.com Ace My Path

🔬 Molluscum Contagiosum ~ #Dermpath #Dermatology #Histology #Pathology