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Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1 rupress.org/jcb/article/22…

The first research paper from our lab is out in Journal of Cell Biology . We show that reticular adhesion formation requires the co-assembly of flat clathrin lattices and integrin avb5 and these structures is inhibited by a cross-adhesion mechanism mediated by integrin a5b1 activation.

.Laura Hakanpää, Leonardo Almeida-Souza et al. University of Helsinki show that reticular adhesions are assembled at flat #clathrin lattices, a process inhibited by #fibronectin and its receptor, #integrin α5β1. bit.ly/3MtMqSQ #Adhesion #Development #integrins

Our paper is out🤩 rupress.org/jcb/article/22… This was such a fun project - and there is more to come! Check out Leo's amazing tweetorial about our key findings ⬇️

Exciting #PhD opportunity at University of Helsinki! We're seeking a dedicated Doctoral Researcher in Molecular and Structural Biology. Dive into cutting-edge research in a collaborative environment. Learn more & apply: bit.ly/PhDUH #AcademicTwitter #PhDChat #SciJobs

News from our CoE, HietakangasLab identify the conserved circadian clock component CWO as a regulator of ribosome biogenesis, UDP-GlcNAc metabolism and tolerance to high sugar diet cell.com/cell-reports/f… Suomen Akatemia | Research Council of Finland @MIBS-Helsinki Institute of Biotechnology (BI) University of Helsinki Congratulations!

We did not get the cover... #NoHardFeelings, though. Nonetheless, i am still very proud of my first 3D adventures with #Blender to illustrate our science. Here is my artistic representation of clathrin coated pits, flat clathrin lattices, and reticular adhesions.

Welcome to the Metabolism seminar next week Friday Dec 8th 9-11am in Viikki. Exciting talks on #lipidomics in human disease by Samuli Ripatti lab and maternal #microbiome #metabolites in development by Mikael Niku lab. ☕️🍪at 8:30 Life Sciences University of Helsinki FIMM HelsinkiUni HiLIFE_Helsinki Institute of Biotechnology (BI)

Be our colleague! 15 days to apply for a position in professor position in integrative physiology. Join us in the happiest country in the world. jobs.helsinki.fi/job/Helsinki-P…

Folate receptor overexpression induces toxicity in a diet-dependent manner in C. Olli Matilainen | Scientific Reports nature.com/articles/s4159… University of Helsinki BioEnvHelsinki @MIBS-Helsinki Suomen Akatemia | Research Council of Finland

I had a blast giving a public lecture on DNA, recombinant DNA technologies and genome editing. Thanks for the Finnish Society for Natural Philosophy for the invitation. The lecture is now on YouTube. youtu.be/p5ToFZfZ7Ic?si…

News from our CoE @jimattil and HietakangasLab show that intestinal nutrient adaptation involves region-specific control of cell size, cell number, and differentiation, out now in Science Advances science.org/doi/10.1126/sc… University of Helsinki @MIBS-Helsinki Institute of Biotechnology (BI) Life Sciences University of Helsinki

Do you want to work in the happiest country in the world and, as a bonus, have really fun colleagues. We have two positions open: -Assistant/Associate Professor in Biochemisty - Lecturer in Genetics jobs.helsinki.fi/job/Helsinki-P… jobs.helsinki.fi/job/Helsinki-U… Spread the word!

Today, a question by a student shook me to the core: "I'm born in Finland from non-European parents. You are my first ever non-white teacher. How is it to do science in europe for someone like us?" I cannot think of a better example why #RepresentationMatters.

Are you a HiLIFE #postdoc? Are you planning to attend a #lifescience conference in 2024? If so, you still have a few days left to apply for the HiLIFE postdoc conference #grant. Apply here by April 2 at 4pm EEST: flamma.helsinki.fi/s/U0HkH FIMM HelsinkiUni @UH_Neuro Institute of Biotechnology (BI) #funding

Are you interested in the process of translating #research into #innovation? Would you like to network with relevant #health and #pharma stakeholders? Then join us at Terkko Health Hub on April 25 for the next Cheese 'n' Wine Innovation Talks! Register by April 22: lyyti.fi/reg/CnW_Meilah…

One more adventure in the world of science communication. #scienceslam Helsinki. Thanks The Science Basement for the invitation and for organising such a fun event. HiLIFE_Helsinki BioEnvHelsinki Institute of Biotechnology (BI) @MIBS-Helsinki youtu.be/NanfIIkCutc?si…

Tomorrow, welcome! 👇

New preprint alert! We describe a new way to detect membrane curvature preference for proteins. The big advantage of our method is that it uses an out-of-the-box equipment (Nanosight Malvern Panalytical), with no modifications. 1/14 biorxiv.org/content/10.110…

It has been 5 years since I started my lab in HiLIFE_Helsinki, University of Helsinki, Institute of Biotechnology (BI), BioEnvHelsinki. Wow, what a rollercoaster! Here are 5 lessons I learned along the way and a reflection on my successes and failures at the end. A thread (1/10)