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The hallmarks of cancer immune evasion dlvr.it/TG8BBS

tidyplots Time to say goodbye to ggplot2?🫡 "a significant reduction of code complexity" vs ggplot2 cran.r-project.org/web/packages/t… Jan Broder Engler bioRxiv 2024 biorxiv.org/content/10.110…

Can’t wait to share this beautiful story from my friend Yu-Jung Chen published on nature Are you also interested in cancer metabolism? Take a look! nature.com/articles/s4158…

Another cool study!Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells: Cell cell.com/cell/fulltext/…

Awesome work! Can’t wait to chat more and see potential collaboration opportunities!

Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery Cancer Discovery. aacrjournals.org/cancerdiscover…

We are hiring! Work in Taiwan with an NIH-scale salary! Please RT!

We report a new role for HIF in the regulation of endogenous retroviruses! It was a big collaborative effort to explore the HIF-mediated transcription, expression, and HLA presentation of ERVs in kidney cancer and leveraging them for immunotherapy cell.com/cell/fulltext/…

The fist lab meeting of Wu lab!#newPI

A fun process to jump into a new topic. By integrating phosphorylation regulome, iMetAct can better predict metabolic preference. Stay tuned for the next step about how we can integrate this with machine learning! Ludwig Cancer Cancer Research Institute

Retroelement-specific tissue resident T cells control tissue resilience and predisposition to inflammation papers.ssrn.com/sol3/papers.cf… Belkaid Lab Alex Wells

Last weeks collection of #immunometabolism discoveries Bims: Biomed News biomed.news/bims-imicid/20… Plenty of interesting papers across innate & adaptive immunity inside

From the April issue: Chronic #ViralMimicry Induction Following #p53 Loss Promotes Immune Evasion brnw.ch/21wRRjh By Charles Ishak Sajid Marhon @DeCarvalho_Lab and colleagues University Health Network Princess Margaret Cancer Centre MD Anderson Cancer Center

Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies dlvr.it/TK8ss6

Biliary tract cancers are aggressive and understudied. This landmark study,led by my brilliant colleague and friend Vindhya Vijay, profiles 63 BTC cell lines with multi-omics and CRISPR screens, revealing subtypes and vulnerabilities. Honored to contribute! Cholangiocarcinoma Foundation TargetCancer Fdn

A new cell line atlas of biliary tract cancers uncovers new subtypes and potential drug targets for better treatment of these deadly diseases. Learn more: broad.io/DepMap-BTCs Mass General Brigham Research TargetCancer Fdn

The Ruscetti Lab had a strong showing at GI Research Day at UMass, with Chaitanya Parikh, Shreya, and Haruka presenting their GI (and non-GI) projects. All the trainees gave fabulous talks, capped off by a great Keynote address by Nabeel Bardeesy. Thanks for organizing Meng-Ju Wu!

Had a great time co-organizing the 2nd annual GI Research Day UMass Chan Medical School ! Honored to invite my former mentor Dr. Nabeel Bardeesy as keynote. He gave a fantastic talk on new targets for hepatobiliary cancers. Grateful to all the attendees. Lots of interesting talks and posters!