🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Excited to share new work from our lab that uncovers mechanisms regulating genome activation in early development. Heroic effort from Hui Chen to spatially map nascent transcriptome, and uncover precocious ZGA. Out online Current Biology. Free access: authors.elsevier.com/a/1fe3c3QW8R%7…

The Department of Microbiology and Immunology at Thomas Jefferson University is hiring new faculty. Please apply to join our collaborative group of researchers! Note: disregard the close date - this position will remain open until filled. jobs.sciencecareers.org/job/618076/fac…

Beyond excited to share our article on #transcriptional #condensates that drive #3Dgenome organization in the #heatshockresponse. Were these HSR condensates primordial #superenhancers? @4Dnucleome Phase Transition Papers @3D_Genome @BioCondensates authors.elsevier.com/c/1g0gg3vVUPK9…

New issue! 📢📢 pubs.acs.org/toc/bichaw/61/… Cover art #2: Matthew C. Good and colleagues Penn University of Pittsburgh show that inducing dimerization of disordered domains to increase valency drives condensate formation. pubs.acs.org/doi/abs/10.102…

Phase separation in viral infections cell.com/trends/microbi…

Great first talk today for Good lab from Mikael V. Garabedian. Sequence determinants for assembly of DNA damage condensates. Collab with Roger Greenberg

Honered to be selected as co-director of @MBLPhys with brangwynnelab 🔬🐙can’t wait!

Our work on microtubule-actin crosstalk is out now in PNASNews Septins capture actin on microtubule lattices and required for protrusive growth cone morphology #CellBio2022 #CytoskeletonWars #ActinMicrotubuleCrosstalk 🧵1/8 pnas.org/doi/10.1073/pn…

Three chemistry heroes! Jennifer Doudna (left), Carolyn Bertozzi (middle) and Frances Arnold (right) have all been awarded the #NobelPrize in Chemistry. Doudna does research on genome editing, Bertozzi works on click chemistry and Arnold works on enzyme engineering.

Fantastic work by Michael Rale and colleages from Sabine Petry featured with pic on the elife homepage: The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC) doi.org/10.7554/eLife.…

Personally, I think being compared to a company that has a bunch of free parafilm shipped to them is just a little unfair.... cen.acs.org/materials/adhe…. Excuse me while I prepare another sequencing shipment... plasmidsaurus Moved on to @parafilmm.bsky.social Noguchi Laboratory Matthew C. Good Chiaki Noguchi

We’re excited to host Jean Gautier (Columbia), Mikael V. Garabedian (Good Lab/UPenn), @ErosLazzerini (NIH), and Tianpeng Zhang (Greenberg Lab/UPenn), for a PCGI Mini Symposium on 3/6, 2-5 PM, BRB Auditorium, Session Topic “Recombination Mechanisms.” See more: events.med.upenn.edu/pcgi/event/771…

Determinants of Disordered Protein Co-Assembly Into Discrete Condensed Phases biorxiv.org/cgi/content/sh… #biorxiv_biophys

Some new work coming out of the Good and Mittal labs! Matthew C. Good Jeetain Mittal Rachel Welles Kandarp Sojitra biorxiv.org/content/10.110…

Our first Members Monday Spotlight features Dr. Angela Crumdy, a Provost’s Postdoctoral Fellow in The Graduate School for Education. Please join us in congratulating Angela on her recent publication in Anthropology & Education Quarterly!

Inspiring Juneteenth lecture at Penn by Freeman Hrabowski III. Important words about purpose and inclusion in science. CAMB Graduate Group UPenn CDB Nice intro by Penn’s own HHMI Hrabowski scholar Mustafa [email protected]

New members changing lab protocols!

Super fun outing with the lab today against backdrop of beautiful Philly skyline Mikael V. Garabedian Wenchao Qian Max Wadley

🧵 I am very excited to share my postdoc project preprint investigating the role of NR4A2, a transcription factor linked to neuropsychiatric disorders, in the establishment of cell type identities in the claustro-insular region of the brain. 1/9 biorxiv.org/content/10.110…

By combining single-cell RNA sequencing with MERFISH spatial transcriptomics, we characterized the transcriptomic identity and spatial organization of cell types and subtypes in the mouse claustro-insular region at high-resolution. 2/9