Macha Nikolski (@machanikolski) 's Twitter Profile
Macha Nikolski

@machanikolski

Computational biology and bioinformatics, artificial intelligence, tango and literature are some of my interests, CNRS - Bordeaux. Opinions are my own

ID: 398066744

linkhttps://bordeaux-bioinformatics.fr/ calendar_today25-10-2011 14:46:23

1,1K Tweet

581 Followers

285 Following

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Even if #remote work has become standard since Covid, #Research needs close-knit teams and in-person collaborations: "remote teams are less likely to integrate the knowledge of their members to produce new, disruptive ideas" - in today's nature

Ewan Birney (@ewanbirney) 's Twitter Profile Photo

I wrote an opinion piece about therapeutic and germline editing for Nature Medicine (rdcu.be/du8Tw; nature.com/articles/s4159…) where I lay out the arguments for a cautious, societally licensed approach to consider germline editing in certain restricted circumstances

EOSC4Cancer (@eosc4cancer) 's Twitter Profile Photo

🎗 February 4th marks #WorldCancerDay, dedicated to raising awareness of the devastating illness and encouraging its prevention, detection, and treatment. To be a part of the battle against cancer, it's essential to understand it. Check out our post on the hallmarks of cancer.

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Advocating for #federated #cancer #data management, our latest publication showcases the ELIXIR Europe roadmap for cancer data infrastructure in Europe for research and precision medicine, uniting data sharing, privacy, and innovation nature.com/articles/s4301…

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Exciting results from our lab by Chalopin Domitille presenting a novel atlas of hepatic innate immune cell atlas in #HCC and identifying THBS1+ Mreg cells as key in disease progression and poor prognosis. #Cancer #bioinformatics #SingleCell #research cell.com/cell-reports/f…

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

[FR] Félicitations à nos jeunes membres d'équipe pour leur participation remarquable à la Battle Département Sciences Biologiques et Médicales sur le thème "IA : la recherche sans chercheur, la médecine sans clinicien". Bravo ! #IA #bioinformatique #éthique #recherche #clinique sbm.u-bordeaux.fr/actualites/des…

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Excited to announce that our DIMet tool Helge Hecht @yguitton44 @Thomas_Daubon to analyse targeted isotope-labeled metabolomics data is now live on Workflow4Metabolomics Galaxy! Explore it under the "Isotopic Studies": workflow4metabolomics.usegalaxy.fr #Metabolomics #Bioinformatics #DIMet

Alexis Groppi 🦋@agroppi.bsky.social (@agroppi) 's Twitter Profile Photo

Join us for our 3rd "Biologie Spatiale" webinar on April 22nd at 11:30am, hosted by the Cancéropôle GSO . Johanna Galvis-Rodriguez of IBGC Bordeaux will present her bioinformatics experience in analyzing MALDI imaging data. Network and discuss! #Bioinformatics #Spata2

Itai Yanai (@itaiyanai) 's Twitter Profile Photo

🔥Just published! What are the principles of plasticity in cancer cells? Studying 7 cancer types we propose that developmental constraints restrict transitions to progenitor & differentiated-like states of adjacent lineages. authors.elsevier.com/a/1jDHoL7PXqQdg Cell Ayushi Patel

🔥Just published! What are the principles of plasticity in cancer cells? Studying 7 cancer types we propose that developmental constraints restrict transitions to progenitor & differentiated-like states of adjacent lineages.
authors.elsevier.com/a/1jDHoL7PXqQdg
<a href="/CellCellPress/">Cell</a> <a href="/AyushiPatel3994/">Ayushi Patel</a>
Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Excited to share that a new #EOSC4Cancer deliverable focusing on enhancing interoperability between clinical trial databases and Clinical Decision Support Systems for #oncology. Special kudos to Majd Abdallah for his work on the #NLP powered matching of patients to #clinicaltrials

Rita Strack (@rita_strack) 's Twitter Profile Photo

I've heard from many that it's not about starting databases and repositories, but about long term funding and maintenance. How do we solve these problems?

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

New publication from our team: DECOMICS – a Shiny app for unsupervised cell type #deconvolution & interpretation of bulk #omic data. Unlock insights from expression or methylation data with state-of-the-art deconvolution and enrichment analysis! #Bioinformatics Slim Karkar

Nature Medicine (@naturemedicine) 's Twitter Profile Photo

A #foundationmodel leverages large-scale medical knowledge to repurpose drugs for diseases that currently lack approved treatments, and provides explanations to support clinicians’ decisions. News & Views from Francesca Grisoni Alaa Bessadok TU Eindhoven nature.com/articles/s4159…

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Excited to present our work on TrialMatchAI, a powerful #AI based tool for matching #cancer patients to #clinical #trials, developed by Majd Abdallah from our #CNRS team, at the AI Meets Cancer Research Symposium 2024! 🧬

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

🎉 A fantastic way to wrap up the year! 🚀 Excited to share our team's latest work led by Chalopin Domitille : SeuratIntegrate R package enhances Seurat v5 with 8 integration methods & batch correction evaluation tools. Check it out! #scRNAseq #Bioinformatics #SingleCell

Itai Yanai (@itaiyanai) 's Twitter Profile Photo

It’s crazy how talking with a science buddy is simultaneously what’s most likely to move the project forward and the thing that’s least prioritized in our schedule.

It’s crazy how talking with a science buddy is simultaneously what’s most likely to move the project forward and the thing that’s least prioritized in our schedule.
Macha Nikolski (@machanikolski) 's Twitter Profile Photo

New preprint from our lab! TrialMatchAI an AI-driven patient-to-trial matching system, with outstanding work by Majd Abdallah. It uses fine-tuned LLMs + medical chain-of-thought reasoning. #LLM #ClinicalTrials #PrecisionMedicine #TrialMatchAI #Bioinformatics arxiv.org/abs/2505.08508…

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

Thrilled to see this fantastic summary of our new preprint on TrialMatchAI! 💥 Huge credit to Majd Abdallah, our team and EOSC4Cancer for making scalable, explainable, and open-source clinical AI a reality. arXiv: arxiv.org/abs/2505.08508… #AI #LLM #ClinicalTrials #PrecisionOncology

Macha Nikolski (@machanikolski) 's Twitter Profile Photo

🧬 New R package from our team! SeuratIntegrate for application&comparison of multiple single-cell integration methods (Seurat, Harmony, LIGER, scVI…)—in Seurat. Led by Domitille Chalopin, developed by Florian Specque 🔗 bordeaux-bioinformatics.fr/seuratintegrat… #scRNAseq #Bioinformatics #RStats