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The ability of adult, somatic, human cells to form novel functional anatomy, with unique behaviors, reveals that this plasticity isn’t restricted to amphibian or embryonic cell properties but a fundamental feature of wild-type cells, requiring no direct 🧬 manipulation to unlock.

We must bring our own light to the darkness. Nobody is going to do it for us. ~ Charles Bukowski on optogenetics 💡 #SolveAging ⌛️

Trained immunity in the bone marrow: Hub of autoimmunity: Cell Stem Cell cell.com/cell-stem-cell…

Chronological versus immunological aging: Immune rejuvenation to arrest cognitive decline: Neuron cell.com/neuron/abstrac…

Mitochondria show a perinuclear clustering pattern at the early phase of somatic cell reprogramming dependent on their retrograde transport and that perinuclear mitochondrial clustering is required for the MET process. In addition, epithelial gene expression is regulated by

If you struggle to do it for yourself, then do it for the people who believe in you.

NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox; science.org/doi/10.1126/sc…

Cancer progression through the lens of age-induced metabolic reprogramming nature.com/articles/s4156…

The earth is a gerontrocity.

Mitochondrial DNA: how does it leave mitochondria?: Trends in Cell Biology cell.com/trends/cell-bi…

Neuronal VPS13D loss drives microglial activation | Nature Structural & Molecular Biology nature.com/articles/s4159…