Our 35th #PDB50structures is RNA polymerase, responsible for transcription of DNA to RNA. Roger Kornberg earned the 2006 Nobel Prize in Chemistry for his work on the complex and determination of the structure: pdbe.org/1i50/3d

Most papers in our field contain some mistakes or weaknesses (surprise, surprise). This is how science works. So what should we do? My view is we should normalise mistakes and normalise discussions of mistakes and weaknesses. And these discussions should be friendly and inclusive

Type your thesis title into app.wombo.art ... what on earth is this monstrosity!

Just received my booster shot, was hoping for Moderna and that's what I got! 😊💉

1. Listen science twitter we need to have a serious talk about what "mechanism" means because it's now basically a meaningless word that is mostly used to reject papers people don't like. But we have a chance to change/improve how we talk about this. Here is how that could happen

Bad study with conclusions that are in conflict with your strongly held beliefs = bad study Bad study with conclusions that confirm your strongly held beliefs = bad study

Had a wonderful time at home with family, kept safe thanks to lots of LFT testing! Back to begin the final stretch of my PhD soon...

When you think you've got a cool result, then a control experiment rushes in to ground you again... nevermind 😅 #phdchat

My paper is out on biorxiv now! We used two-colour STORM to image transcriptionally active single chromatin fibres alongside RNA pol II at super-resolution 😁

Pursuing a statistics PhD at Harvard was one of the best decisions of my life. Statistical thinking is a superpower that gives you powerful frameworks for simplifying the complexity of daily life. THREAD: 8 principles I learned while studying statistics that might help you too

PhD thesis submitted! Resisting the urge to read through again and look for any typos I might have missed...

Active chromatin images 😁

The revised version of our paper with peer review comments is now up! (Funny getting that "do you want to read the article first before retweeting?" notification for this...)

An updated manuscript with the reviewer's comments taken into account is now available! Thank you to our reviewers for giving constructive commentary, our paper will undoubtedly be improved as a result. Doing some exciting recommended experiments at the moment🤞

I passed my viva!! 😁 In typical fashion, I went straight back to work... 😅

One of my first articles, published with The Microbiome Times 😊 microbiometimes.com/exhaled-breath…

Another one of my articles has been published 😊

Great to see our second paper out as a pre-print! Click to see how histone mods are arranged along a transcriptionally single chromatin fibre at super resolution... 🧬

Article I co-wrote out now: 🦠🧫