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Medulla only! Some diagnoses can be made in medulla only biopsy ⁃ Myeloma kidney ⁃ Light/heavy chain deposition disease ⁃ Amyloid ⁃ Crystals ⁃ sometimes ATN, interstitial nephritis, pyelonephritis Case showing large number of uric acid crystals in medulla:Urate nephropathy

For Kidney Health Advocates- lets all get on the same page: 1) only <5% of incident CKD is caused by HTN;2) progression of CKD can be slowed by treatment of HTN when proteinuria is concomitantly present; 3) HTN is mostly consequent to CKD, not caused by CKD.

Engineered antigen-specific T regulatory cells suppress autoreactivity to the anti-glomerular basement membrane disease antigen doi.org/10.1016/j.kint… #OpenAccess #glomerulonephritis

The intelligent podocyte: sensing and responding to a complex microenvironment nature.com/articles/s4158…

kireports.org/article/S2468-… Podocyte number per glomerulus predicts progressive CKD independent of clinical characteristics (GFR and proteinuria) or other microstructural pathology (glomerular size or nephrosclerosis)!

Don’t miss this Systematic Review and Meta-analysis of Initial Treatment for #LupusNephritis of the Grupo Latino Americano de Estudio de Lupus (GLADEL)! ⏩ The combined therapies may represent a more effective approach in the management of #LN 💊Especially the combination of

Nefrología H. La Paz Madrid Los PLA2r Han cambiado la forma de diagnosticar y tratar algunas Nefropatia membranosas, aunque todavía nos queda mucho por aprender de ellos. En este artículo se analiza la dinámica de los PLA2r en los tres grandes EC y su repercusión en la evolución

Induction Therapy for Class I/II Lupus Nephritis with Glucocorticoid Monotherapy associates with Higher Relapse and Poorer Kidney Outcomes doi.org/10.1093/ckj/sf…

One of the biggest issue when treating #MembranousNephropathy is we have to secure a good dose of rituximab. 💧Urinary loss of RTX >2mcg/mL is associated with lower clinical and immunological response ➡️ treatment failure. NDT #MembranousNephropathy

🫘👍Managing Secondary TMA academic.oup.com/ndt/advance-ar… NDT Hans-Joachim Anders

Kidney #Transplant Outcomes in #Recurrent Versus #DeNovo IgA Nephropathy #IgAN #VisualAbstrct by Pallavi Prasad MD DNB kireports.org/article/S2468-…

Now online in NDT Acute post-streptococcal GN (in children) - treatment standard 🧐 Pathophysiology, diagnosis, outcome prediction, and management standard ▶️academic.oup.com/ndt/article-ab…

🤔What if IgA nephropathy is more than just mesangial IgA deposits?🫘 🧬From genes➡️ gut➡️ glycosylation➡️ glomeruli, the updated 4-hit model now meets autoantibodies, complement & plasma cell targets🎯 Must-see pathway map👇 🔗doi.org/10.1093/ckj/sf…🆕 #Nephrology #IgAN #MedX

Time is critical in AAV: dampening kidney inflammation prevents damage Why not target effector T cells - leave other T cells alone? Our paper in @NDTSocial defines IL-7Ra as a target doi.org/10.1093/ndt/gf… Anti-IL-7Ra Abs are in Phase 2 trials - alopecia Q32 Bio Inc. ?an AAV therapy

GlomPedia can now be accessed via the web @ glompedia.org Stay ahead in the field of glomerular diseases with this must-have resource. #GlomPedia #GlomCon

🙌🏻 GlomPedia Available through: 🛜 glompedia.org!! #GlomPedia #GlomCon GlomCon Sonia Rodríguez-Ramírez

Membranous nephropathy has undergone a paradigm shift due to the discovery of unique MN antigens. MN has gone from idiopathic to ➡️ primary vs. secondary ➡️ where an antigen can be detected in ~80% of MN. This is a comprehensive review of each antigen. nature.com/articles/s4158…

Some well formed "eye lashes" on these capillary loops in a case of AL-amyloidosis. Podocytes getting skewered by the spicules in the EM. #renalpath #pathtwitter #nephrology.

The 2025 British Society for Rheumatology management recommendations for ANCA-associated vasculitis ⏩GPA and MPA ⏩ subglottic stenosis and ENT ⏩EGPA ⏩Service specifications ⏩Patient education and support. academic.oup.com/rheumatology/a…