Maha Rahim, PhD ⁦SpitzerLab⁩ on Immune system retaliation of #immuno-Oncology drugs at #breastcancer retreat ⁦UC San Francisco⁩

Excited to share our new paper in Nature Medicine in which we demonstrate that tumor burden dynamically reshapes the composition and function of the immune macroenvironment. Here are some of the main highlights! go.nature.com/3c4CjzP 1/7

In our lab, we celebrate these facts: All people are equal. Hatred, racism and violence have no place in our community or the world. You don’t always need a p-value to know that something is right. MS

#BlackHistoryMonth We're highlighting the exceptional work of #BlackinMicrobiome researchers. Dr. Joel Babdor (he/him), postdoc, Spitzer Lab UC San Francisco, co-founder of #BlackInImmuno, is investigating system level interactions between the microbiome and human immune system. pubmed.ncbi.nlm.nih.gov/31315057/

I’m super excited to share what I’ve been working on for the last three years: a new deep learning algorithm to accurately identify cells in imaging data! Our method works across image platforms, tissue types, and species with no fine-tuning required. 🧵 biorxiv.org/content/10.110…

Excited to share our new paper in Immunity led by @laurenlevine2 & @inflammatorydc in collaboration with Jeff Rathmell. We profiled CD8 T cell metabolism during infection at single cell resolution to reveal intriguing transient metabolic states authors.elsevier.com/a/1cj2a3qNrUmQ…. 1/8

Immunity is coordinated across tissues. A localized antitumour immune response cannot exist without continuous communication with the periphery. In our new Nature Reviews Cancer review we outline the importance of a holistic view of cancer and immunity: rdcu.be/cioLT

Excited to share the latest preprint with Michael Angelo! While imaging studies often focus on cell objects, images capture significant info outside of cells. Enter Pixie, a pipeline for the quantitative annotation of both pixel and cell level features🧵biorxiv.org/content/10.110…

Tumor-draining lymph nodes play an important role in responses to cancer #immunotherapy: authors.elsevier.com/sd/article/S00…

#Immunotherapy can activate tumor-fighting T cells in lymph nodes near a tumor, suggesting that leaving lymph nodes intact could boost efficacy against solid tumors. bit.ly/3YZDeKg

Excited that my work with Trine Line Hauge Okholm Kyle Jones & SpitzerLab is out! We leveraged spatial biology to study CD8T cells in lymph nodes, their role in anti-tumor immune responses and disruption by metastasis. Explore the images on Enable Medicine! app.enablemedicine.com/share/vis/q4_b…

Leaving lymph nodes intact until after #immunotherapy may boost efficacy against solid tumors, a UC San Francisco Gladstone Institutes study finds: "Taking them out before immunotherapy treatment may be throwing the baby out with the bathwater,” author Matt Spitzer says. ucsfh.org/3yWlF2Z

Stop by booth 1259 at #AACR23! Learn how we are moving from images to insights to explore complex questions about human disease that are being answered for the first time. hubs.ly/Q01KgS-W0 #Oncology #SpatialBiology

That's no moon... May the 4th be with you! Check out this sample from the lab of Fernando Guimaraes at UQ News imaged in our lab with @akoyabio #Phenocycler. #BeatCancer #Spatialbiology #Bioinformatics

@erikreinertsen I have pdf versions of "Intro to R" and "The R Book" if you're interested, the former being decently useful.

Scientific research meets thrilling melodrama #DNAday amazon.com/dp/074321630X/…

"Don't let the apron deceive you; bakers are mad scientists" ed.ted.com/lessons/the-ch…

Hot ice cream and rotovapping orange peels. The Biophysics of Molecular Gastronomy cell.com/abstract/S0092…

A double entendre:The Really Big One gets my vote as best written science story I've ever read newyorker.com/magazine/2015/…

my 1st tweet and 1st step in our long journey to understand healthy nutrition cell.com/abstract/S0092…