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Conclusions of a statement of ALD EXPERTS on MetALD: 🔸"Met" should include >1 risk factor: alcohol itself favors metabolic syndrome. 🔸Alcohol thresholds need prospective studies including biomarkers. 🔸Trials testing therapies for MetALD are needed. t.ly/L2JWE

2024: a year of biomarker research #LiverTwitter ➡️Next 12 days I will post a summary of publications and collaborations, one month per day. JANUARY: Kicked off with a review on algorithms for early fibrosis detection, including the growing role of AI: thieme-connect.com/products/ejour…

Recap of 2024 for #LiverTwitter 📅FEBRUARY is omics month GALAXY #MicrobLiver 📰Journal of Hepatology review: opportunities & barriers for omics as biomarkers 💪Powerful technologies which we are only now starting to explore in clinical care 🔗journal-of-hepatology.eu/article/S0168-… ida villesen

My #LiverTwitter recap of 2024, 3/12 MARCH was kick-off month for LiverAim ‼️ Learn more here: liveraim.eu LIVERAIM will set the direction for biomarker research & implementation, including POSITIVE: the largest RCT in hepatology, with n=100,000 Stine Johansen

What happened in APRIL 2024? Month-by-month for #livertwitter Landmark for evido.health 🥇One of the first companies to receive CE certification for LiverPRO under 🇪🇺IVDR Later @KatrinePLindvig published LiverPRO derivation & validation 🔗thelancet.com/journals/langa…

I recap 2024, month-by-month #LiverTwitter 🗓️MAY: AASLD Practice Guidance➡️risk stratification & management of PHT & varices in cirrhosis 👉From A to Z on 🔝 elastography and blood based NILTs Read here👇 journals.lww.com/hep/fulltext/2… AASLD Doug Simonetto, MD Guadalupe GarciaTsao

EASLnews Aleksander Krag Sven Francque APDP Diabetes Paul Brennan Maja Thiele Jörn Schattenberg Naim Alkhouri Maru Rinella MD FattyLiverAlliance Francesco Paolo Russo Ajay Duseja Arun J. Sanyal Dr Maja Thiele presenting our forthcoming work on the SLD patient trajectory. How to case find? I think we clearly need "Implementation of a liver health check in people with type 2 diabetes" thelancet.com/journals/langa… #SLDsummit

Today, we were honored to host Jane Kraglund (regional director), Bo Libergren (chairman, regional council) and the OUH direction to talk about patient-centered research at a high international level 🎯We do it FOR and WITH our patients OUH Odense Svendborg Region Syddanmark

What happened in 2024 #LiverTwitter ? 🗓️JUNE was #EASLcongress month! 💡 highlight of the year! I chaired a session on MetALD with Moreno Christophe and Helle Lindholm Schnefeld Mads Israelsen Johanne Kragh Hansen, MD, PhD presented new findings from FLASH - Liver Research

This is so far the most interesting article of 2025: 🚰The real-world leaky pipeline when screening for fibrosis and cirrhosis: 🤏Less than 11% of VA patients with FIB-4≥3.25 could/would enter into elastography case finding program 🔗bmchealthservres.biomedcentral.com/articles/10.11… #livertwitter

🧵Just released! Our The Lancet Gastroenterology & Hepatology review explores the latest AUD management from a gastro/hepatology perspective 👉authors.elsevier.com/c/1kc078nByrCi…. ⬇️ Juan Pablo (JP) Arab, MD  Ramon Bataller Lorenzo Leggio MASLD Research Center UCSD Gastroenterology Facultad Medicina UC #LiverTwitter ALEH AASLD EASL Education

Challenge for #LiverTwitter : Monitoring regression/progression on resmetirom & deciding on alternative treatments ▶️AASLD provided guidance ▶️We commented on the role of LSM: doi.org/10.1097/HEP.00… ‼️Random variation in LSM >25% ‼️Consider overall benefit (e.g., GLP-1)

We made the cover Stine Johansen Mads Israelsen 👏 HEPATOLOGY Journal #LiverTwitter journals.lww.com/hep/fulltext/2…

The Baveno Cooperation: an EASL Consortium Research Committee Baveno VIII Pre-Symposium, here we go! 👍 103 members watching online 👉 High interest in designing clinical studies on PH! #LiverTwitter

🚀#LIVERAIM is on the move! Biomarker analysis for early liver fibrosis detection has started at #CORELAB of Hospital Clínic on 22k+ serum samples from general and high-risk populations. 🔎Watch how science is shaping the future! #livertwitter Innovative Health Initiative IDIBAPS EASLnews

Burden of cirrhosis in emergency dpt exceeds COPD and heart failure. 🚨51% of ED cirrhosis are ALD 🚨12% died within 90-days from discharge to home if decompensated CGH cghjournal.org/article/S1542-…

Impressing: PathAI obtains EMA qualification as first AI tool to read biopsies in MASH trials 👉Context of use: determine a disease activity biomarker based on steatosis, ballooning, lobular inflammation & fibrosis stage ☝️The tool is an AID to central pathologist #livertwitter

Fantastic meeting of the Study of Alcohol-related LiVer disease in Europe EASLnews study of ALD in Europe We discussed 🤝track hub at #EASLcongress 👨‍💻SALVE database 🛜New webpage launch 💪Future collaborative projects 👉How to battle stigma 🥇New members

📢ESSENCE out now and it's a game changer for hepatology! GLP-1 RA improves histology AND metabolic health in MASH F2-3 fibrosis: 📍Absolute difference in fibrosis reduction of 15% = NNT 6.7 📍63% resolution of MASH vs 34% placebo. Wauw #LiverTwitter 🔗nejm.org/doi/full/10.10…

🚨Liver Screen Study final results ⭐️+30.000 patients Tremendous effort. 👏congratulations to all the investigators. Isabel Graupera Maja Thiele #EASL2025