Malek Ayoub, MD (@malekayoubmd) 's Twitter Profile
Malek Ayoub, MD

@malekayoubmd

PGY-3 @WashUIMRes| Interested in #Diversity, #GI #IBD #MentorshipinMedicine |#FirstGen| #Liverpool fan ⚽

ID: 1284534560156536834

calendar_today18-07-2020 17:05:36

161 Tweet

430 Followers

828 Following

Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

Shivani Shah Mattay Digestive Disease Week SPARC IBD Study Matthew Ciorba MD @krithika_shenoy Xiuli Liu @wusm_pathology @WUGastro @WashUIMRes @WashUFWIM Aldanah Althwanay, MD| الدانة الثويني Rahul Peravali Women In Endoscopy | WIE Also other mentees from @WashUIMRes Malek Ayoub, MD also on Mentors-in-Med grant, data at ACG2024, #ScottAnderson GLP-1 analog data in IBD at ACG2024 & #ShannonCoombs poster #DDW2024 on postsurg disparities rural/urban in IBD

<a href="/ShivaniMattay/">Shivani Shah Mattay</a> <a href="/DDWMeeting/">Digestive Disease Week</a> <a href="/SPARCIBD/">SPARC IBD Study</a> <a href="/CiorbaGI/">Matthew Ciorba MD</a> @krithika_shenoy <a href="/XiuliLiu1/">Xiuli Liu</a> @wusm_pathology @WUGastro @WashUIMRes @WashUFWIM <a href="/aalthwanay1/">Aldanah Althwanay, MD| الدانة الثويني</a> <a href="/RahulPeravali/">Rahul Peravali</a> <a href="/WomeninEndo/">Women In Endoscopy | WIE</a> Also other mentees from @WashUIMRes 
<a href="/MalekAyoubMD/">Malek Ayoub, MD</a> also on Mentors-in-Med grant, data at ACG2024, #ScottAnderson GLP-1 analog data in IBD at ACG2024 &amp; #ShannonCoombs poster #DDW2024 on postsurg disparities rural/urban in IBD
Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

Celebrating 2 recent successes in the basic-clin/translational-rad collab group @IbdWustl WashUMedMIR with Siyan Cao "Stewart", MD PhD KO8 NIDDK on XBP1 pathway~anti-IL23 response biomarker & David Ballard Radiology on PET-MR quantification of disease activity/response in perianal CD

Celebrating 2 recent successes in the basic-clin/translational-rad collab group @IbdWustl <a href="/MIRimaging/">WashUMedMIR</a> with <a href="/Siyan_Cao/">Siyan Cao "Stewart", MD PhD</a> KO8 <a href="/NIDDKgov/">NIDDK</a> on XBP1 pathway~anti-IL23 response biomarker &amp; <a href="/DavidBallardMD/">David Ballard</a> <a href="/radiology_rsna/">Radiology</a> on PET-MR quantification of disease activity/response in perianal CD
Abby Spencer, MD, MS, FACP (@abbywuim) 's Twitter Profile Photo

🥳🥼🩺🥼🩺🤳🤳Only thing better than @WUDeptMedicine @WashUIMRes rounds w our awesome team is running into another excellent team of #MedEd stars and awesome residents! What a treat! #SupportTrainees

🥳🥼🩺🥼🩺🤳🤳Only thing better than @WUDeptMedicine @WashUIMRes rounds w our awesome team is running into another excellent team of #MedEd stars and awesome residents! What a treat! #SupportTrainees
Malek Ayoub, MD (@malekayoubmd) 's Twitter Profile Photo

Grateful for the incredible mentorship and support from Parakkal Deepak MD, MS, FACG throughout my journey! Couldn’t have asked for a better mentor. I’m lucky to have someone who believes in me and inspires me to keep pushing forward! #Mentorship #ACG2024

Grateful for the incredible mentorship and support from <a href="/P_DeepakIBDMD/">Parakkal Deepak MD, MS, FACG</a> throughout my journey! Couldn’t have asked for a better mentor. I’m lucky to have someone who believes in me and inspires me to keep pushing forward! #Mentorship #ACG2024
bioRxiv SysBio (@biorxiv_sysbio) 's Twitter Profile Photo

Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease biorxiv.org/cgi/content/sh… #biorxiv_sysbio

Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

🤩 to 🚀 new chapter as Co-Director WashU Medicine Inflammatory Bowel Disease Center WashU Medicine Division of Gastroenterology WashU Medicine. 🙏 to Matthew Ciorba MD Director of the IBD Center, for continued mentorship & sponsorship since joining post-IBD fellowship in 2017. Plans for next 5 yrs of excellence in #IBD care & research in 🇺🇸 & 🌎

🤩 to 🚀 new chapter as Co-Director <a href="/WashUMedIBD/">WashU Medicine Inflammatory Bowel Disease Center</a> <a href="/WashUMedGastro/">WashU Medicine Division of Gastroenterology</a> <a href="/washumedicine/">WashU Medicine</a>. 🙏 to <a href="/CiorbaGI/">Matthew Ciorba MD</a> Director of the IBD Center, for continued mentorship &amp; sponsorship since joining post-IBD fellowship in 2017. Plans for next 5 yrs of excellence in #IBD care &amp; research in 🇺🇸 &amp; 🌎
Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

A real beast Siyan Cao "Stewart", MD PhD ! Proud to call him a colleague and close collaborator where we bounce ideas back-forth. And to top it all, he also runs ultra marathons on weekends and medals in them!

Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

Interesting paradigm of adding GLP1RAs in patients with #IBD with positive clinical outcomes reported from multiple centers, whether impact on VAT compartment &/or epithelial healing, to be studied in upcoming trial funded Helmsley Charitable Trust led by #LouisCohen myself & Andres Yarur

Interesting paradigm of adding GLP1RAs in patients with #IBD with positive clinical outcomes reported from multiple centers, whether impact on VAT compartment &amp;/or epithelial healing, to be studied in upcoming trial funded <a href="/HelmsleyTrust/">Helmsley Charitable Trust</a> led by #LouisCohen myself &amp; <a href="/AndresYarur/">Andres Yarur</a>
Malek Ayoub, MD (@malekayoubmd) 's Twitter Profile Photo

Thrilled to be presenting at #DDW2025 this week—grateful for the opportunity to share our work on biologics and real-world outcomes in IBD, including perianal Crohn’s. Immense thanks to my mentor Parakkal Deepak MD, MS, FACG for his guidance and support! #AGAGastroSquad 🔥

Thrilled to be presenting at #DDW2025 this week—grateful for the opportunity to share our work on biologics and real-world outcomes in IBD, including perianal Crohn’s. Immense thanks to my mentor <a href="/P_DeepakIBDMD/">Parakkal Deepak MD, MS, FACG</a> for his guidance and support! #AGAGastroSquad 🔥
Michael Chiorean (@mchiorean4) 's Twitter Profile Photo

Ayoub et al - retrospective admin database study suggesting similarity btw 2nd line therapies at 1 and 2 years in peri-anal #crohnsdisease after exposure to IFX. Hard to position advanced therapies based on this given the multiple confounders ##DDW2025 #IBD

Ayoub et al - retrospective admin database study suggesting similarity btw 2nd line therapies at 1 and 2 years in peri-anal #crohnsdisease after exposure to IFX. Hard to position advanced therapies based on this given the multiple confounders ##DDW2025 #IBD
Aline Charabaty, MD, FACG, AGAF (@dcharabaty) 's Twitter Profile Photo

#DDW2025 What’s after IFX for perianal Crohns ? 🔺Real world 😮No difference in abx use, 🏥, ER visits, perianal surgeries) at 1 yr between ADAL, VDZ, UST, RIZA, UPA 💬 Is that your experience? What is your preferred 2nd line for pCD? 💬Time to combine advanced therapies?

#DDW2025 What’s after IFX for perianal Crohns ?

🔺Real world 
😮No difference in abx use, 🏥, ER visits, perianal surgeries) at 1 yr between ADAL, VDZ, UST, RIZA, UPA

💬 Is that your experience? What is your preferred 2nd line for pCD?
💬Time to combine advanced therapies?
Parakkal Deepak MD, MS, FACG (@p_deepakibdmd) 's Twitter Profile Photo

For me the most impactful data Florian Rieder #DDW2025 was interim analysis of #Stenova 1st stricturing CD trial showing esp 200 qd dose: - Safety/tolerability prim. endpoint - Improvements in SES-CD, scope passability & MRE findings - Symptom improvement - Transcriptional changes

For me the most impactful data <a href="/IBD_FloMD/">Florian Rieder</a> #DDW2025 was interim analysis of #Stenova 1st stricturing CD trial showing esp 200 qd dose:
- Safety/tolerability prim. endpoint 
- Improvements in SES-CD, scope passability &amp; MRE findings
- Symptom improvement 
- Transcriptional changes
Malek Ayoub, MD (@malekayoubmd) 's Twitter Profile Photo

Grateful beyond words—thank you, Dr. Deepak for your unwavering support, mentorship, and belief in me throughout this journey. I’ve learned so much from your example and look forward to carrying those lessons with me into fellowship and beyond.

Malek Ayoub, MD (@malekayoubmd) 's Twitter Profile Photo

Thank you so much, Dr.Parakkal Deepak MD, MS, FACG Your mentorship has meant the world to me, both in research and in life. I’m incredibly lucky to have learned from you.