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And now a contribution from HZB-MXde by Uwe Müller on Trends in macromolecular crystallography at #InSynX

Manfred Weiss at the IUCr-2029 table at the DGK conference in Bayreuth

Everybody, please stop by and pick up your IUCr-2029 badge Conventus GmbH

Get all the news about IUCr-2029 at the General Assembly tomorrow. Or stop by at the table for a chat.

The #DGKconference in beautiful sunny Bayreuth had 4 days of informative lectures interspersed with fun social evenings bringing people from diverse fields together, ending successfully with a interview with IUCr by Florian Meurer 📯 (Our new Chair🥳) and Tina Weigel (ex-Chair❤️)

Save the date: Wednesday, 24. 04 is the monthly Colloquium by Zoom, organized by African Synchrotron (4PM GMT+2) "The problem of protein folding: how it may go wrong and how cellular machines make it go right" by Paolo De Los Rios from EPFL Registration: us02web.zoom.us/meeting/regist…

Out now, in Structural Biology: A new paper from Neumann et al, with contributions from Jan Wollenhaupt and Manfred S. Weiss. Read all about it here: doi.org/10.1107/S20597… BESSY@HZB Helmholtz-Zentrum Berlin

Hot of the press in ChemMedChem: A new paper with contributions from Manfred S. Weiss and Jan Wollenhaupt, featuring data collected at BL 14.2. It describes new Furin inhibitors partly based on fragments, even making front cover! doi.org/10.1002/cmdc.2… Helmholtz-Zentrum Berlin BESSY@HZB

🗓️We've updated our logo and our calendar! For more information please refer to the IUCr website where you can find out about bursaries, abstract deadlines and registration ↓ iucr.org/calendar/calen…

🔔Meeting support available for #EarlyCareerScience Early registration & bursary application deadline for the International School on Fundamental Crystallography 7th MaThCryst School in Latin America >> 24 June 2024! even3.com.pe/e/ISFC2024-7Ma…

Manfred S. Weiss will be attending the ACA conference in Denver next week. Anybody interested in IUCr-2029 can approach him and get the latest news. IUCr2023 DGK AK Junge Kristallographen/Young Crystallographers Swiss-crystallography

Hot off the press: a new paper in the European Journal of Medicinal Chemistry, with contributions from Manfred S. Weiss. Read all about the structure-based mapping of the KDM4D binding pocket here: doi.org/10.1016/j.ejme… Helmholtz-Zentrum Berlin BESSY@HZB Elsevier Chemistry

Out now in Structural Biology : A new paper with contributions from Manfred S. Weiss, about crystallographic fragment screening against a protein from Mycobacterium tuberculosis. Read all about it here: doi.org/10.1107/S20597… BESSY@HZB Helmholtz-Zentrum Berlin

Manfred S. Weiss is at the ECM Meeting in Padova (Italy). DGK Swiss-crystallography IUCr2023 IUCrJ

From the ECM34.Manfred S. Weiss

Exiting news: a new publication describing the HZB-MX F2X fragment-screening facility in all aspects is out in Applied Research. Read all about our facility here: onlinelibrary.wiley.com/doi/10.1002/ap… Congratulations to Tatjana, Melanie and the entire F2X-team. Helmholtz-Zentrum Berlin BESSY@HZB

Just published in Structure: A review with contributions from Manfred S. Weiss, detailing the challenges, state-of-the-art and future directions for integrated structural biology at European research infrastructure sites. doi.org/10.1016/j.str.… Helmholtz-Zentrum Berlin BESSY@HZB Instruct-ERIC

Publications aplenty. 2024 abounded in reviews related to FBLD - structure-based methods, covalent fragment strategies, targets, PROTACs, and more practicalfragments.blogspot.com/2024/12/review… Prof Sally-Ann Poulsen🌻 Manfred S. Weiss ACS Publications Magnetic Resonance News Diamond Light Source

Where to House Big Data on Small Fragments? | ChemRxiv - go.shr.lc/4j3oXY1

Here is an interesting quote from practicalfragments.blogpsot.com : "By far the biggest winner among methods has been X-ray crystallography; it jumped from sixth place in 2011 to first place in both 2019 and 2024." Yeah!