🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

📢 Please RT! Thrilled to announce the International Colloquium ‘Epi/genetic architecture of psychiatric disorders’, with top speakers on Monday Oct 3, 2022, at the Pierre & Marie Curie campus in Paris. More information and free registration at epigenpsy.sciencesconf.org

A PhD position is available in my lab starting in January on a project about Sudden Unexplained Death in Epilepsy (SUDEP) in mouse models. Here the link for applying (with more info on the project): emploi.cnrs.fr/Offres/Doctora… Please share. Best #PhD #Position

Great discussions last week in Amsterdam at the annual hybrid meeting of the SCN1A-UP! EJP-RD consortium (ejprarediseases.org/scn1a-up-thera…) about development of pre-clinical therapeutic approaches for Dravet syndrome. Thank you Eleonora Aronica for hosting it.

Lab members (Tiffany Migevent, Jenny Rusina, Fabrice Duprat and Cyril Lhopitalier) at the Dravet syndrome EDSAT meeting in Madrid: great discussions and interactions!

Registration for the 2nd #Channelopathy Meeeting in Tübingen is now open 👇 Genetic epilepsies and other neuronal ion channel disorders: Mechanisms and therapeutic perspectives ‼️ See you in Tübingen in October (4th to 6th) 😊 #Epilepsy 💜 #Genetics 🧬 ec.europa.eu/eusurvey/runne…

REVIEW Here our recent overview on “Voltage Gated Sodium Channels in genetic epilepsy”. I hope you will find it useful ! onlinelibrary.wiley.com/doi/full/10.11…

🗓️ Next March, EnfermerasMadrid will host the European Dravet Syndrome Conference 2024 🧬🔬, an international event 🌍 for experts in #Dravet 💜. ⚠️If you are a researcher, submit your #abstract before October 15th‼ 👉 dravetconference.com 👈

Open postdoctoral position in my lab: emploi.cnrs.fr/Offres/CDD/UMR…

Deadline for abstract submission to the #Grindelwald meeting on #SodiumChannels is very soon: 18 Nov. You don't want to miss this unique scientific event!

Goodbye Bill. I had a very good time as a postdoc in the lab of a great scientist who accomplished so much and mentored so many people: a melting pot of scientific projects and great people from all over the world. RIP William A. "Bill" Catterall.

Great interactions at the European Dravet Syndrome Conference 2024 in Madrid, Spain. Here with my postdoc Jacqueline "Jacqui" Heighway, and Jacqui receiving the award of best oral presentation from the hands of Helen Cross, president of the ILAE. Congrats!

New lab's paper. NaV1.1/Scn1a phenotype: homozygous patient's gain-of-function variant causes life-threatening apneas and brainstem depolarization; responds to sodium channel blockers. pnas.org/doi/10.1073/pn…. With S.Cestele, E.Tolner, Andreas Brunklaus , A.van den Maagdenberg, et al.

Congrats to Martina Simonti : Best Oral Presentation Award at the meeting of the Life Sciences doctoral school of the University Cote d'Azur - Nice - France !

Happy to share our latest paper (pnas.org/doi/10.1073/pn…) on preictal dysfunctions in Dravet syndrome that paradoxically lead to Low-Voltage-Fast (LVF) seizures and allow seizure prediction. Great work of Fabrizio Capitano and collaborators

🚀 Join our study & please retweet Refine semi-automated tools for genetic variant classification. 👩‍⚕️ Who? Medical pros & researchers 🧬 What? Classify variants using novel interfaces 💡 Why? Shape the future of decision support in genetics Link: go.uth.edu/geneportalstudy

In the first talk of the is series Massimo Mantegazza will not only share exciting new data on Nav1.1 and its role in pathophysiology, but he will also remember Dr. Bill Catterall and his contributions to the sodium channel field. So be prepared for a special seminar next week!

After the seminar is before the seminar! Following the very successful start mark your calendars for the next #WWSCS given by Dr. Rajesh Khanna of the KhannaLabUF on Oct 29 on “The path to drugging Nav1.7: Why aren’t we there yet?" Visit sodiumchannelsemianrs.org for more info and the login link.

Job alert. Postdoctoral position in my lab. Pathological mechanisms and therapies of mouse models of epileptic encephalopathies: in vivo electrophysiology, silicon probes neuropixels, behaviour, pharmacology. emploi.cnrs.fr/Offres/CDD/UMR…

Paper Alert! New paper of the lab: Neurodevelopmental defects in Dravet syndrome Scn1a+/− mice: Targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality doi.org/10.1016/j.nbd.…. Great job of Lara Pizzamiglio, former postdoc, and co-authors.

🧠 Exploring new treatment approaches for DEEs at #EDSC2025! Massimo Mantegazza (CNRS, University Côte d’Azur) introduces the mechanistic insights behind Developmental & Epileptic Encephalopathies (DEEs). 🔬 Understanding the science behind treatment is key to innovation!