
Marc Mansour
@marcrmansour
Professor of Haematology at UCL Cancer Institute/Great Ormond Street ICH, investigating mechanisms of leukaemia formation and novel leukaemia therapies
ID: 2884953820
https://www.ucl.ac.uk/cancer/research/department-haematology/leukaemia-biology-research-group 19-11-2014 22:52:25
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Great collaboration with Marc Mansour yardena samuels Swanton Lab @SineRekerHAdrup UCL Cancer Institute and Achilles Therapeutics funded by Horizon 2020 News

New consultant post available in the CAR-T clinic at UCLH working with me, Claire Roddie Maeve O'Reilly . gbr01.safelinks.protection.outlook.com/?url=https%3A%…

If you’re going to be at the European Hematology Association annual meeting in Madrid this week and want to see exciting unpublished basic/translational research, then check out the Mol Hem Workshop from 8-12 on Fri 14th ehaweb.org/congress/eha20…

We are looking for a post-doc with a background in immunology to work on the impact of RAS oncogenic signaling on the interaction of lung cancers with the immune system. Fully funded four year position at Francis Crick Institute in London. #Crick crick.wd3.myworkdayjobs.com/External/job/L…




Focal deletions of noncoding regions in cancer genomes can have unexpected consequences. Out now in Blood Journal, we’ve discovered an intriguing mechanism of oncogene activation whereby focal deletion of a ‘promoter tether’ leads to aberrant expression of IRX3 in T-ALL. Thread👇

Recurrent deletions of an inert genomic region in FTO releases a ‘promoter tether’ enabling a potent oncogene to interact with a distal super-enhancer - an intriguing mechanism of IRX3 activation in T-ALL. Please see thread of our new work led by the brilliant Sunniyat Rahman : 👇

Another step closer to understanding T-ALL in children & adults. 💡 A team of scientists led by Sunniyat Rahman and Marc Mansour have found that DNA deletions can remove a 'promoter tether,' allowing the oncogene IRX3 to switch on and drive cancer. 🔗: ashpublications.org/blood/article/…




🧪 Please share! The Proteomics Team at UCL Cancer Institute is hiring a Computational Scientist to carry out + develop computational analysis of multi-omics data w/ focus on proteomics and phosphoproteomics. Apply by 13 Jan: bit.ly/3VMN7Mi Questions to Silvia Surinova

Great work Nicola maciocia Paul Maciocia with this excellent review of state-of-the-art CART approaches for T-cell cancers Blood Advances UCL Cancer Institute UCLH ashpublications.org/bloodadvances/…

T-ALL Biology: Charles Mullighan, Marc Mansour, and Daniel Herranz will address this topic in a plenary session at the AACR Special Conference on Acute Lymphoblastic Leukemia (March 7-9, San Diego). Learn more: brnw.ch/21wQ8ag #aacrALL25 Charles Mullighan Marc Mansour


📣 MEET THE FACULTY OF #ESHALL2025! Register now & Join them in Malahide (Dublin) 🇮🇪 on May 22, 2025 ➡ bit.ly/4cy9jAS 4th Translational Research Conference on ACUTE LYMPHOBLASTIC LEUKAEMIA Chairs: Kathrin Bernt, Jan Cools, Dombret Hervé, Ulla Wartiovaara-Kautto #ESHCONFERENCES #LEUsm


We are looking for a talented postdoctoral bioinformatician The Dawson Lab to work with us on single cell multiomics incorporating lineage tracing and spatial technologies- we specifically want someone curious, fearless with a licence to innovate!! nature.com/naturecareers/…

So proud of this incredible work from Gaurav Agarwal from our group with help from many fantastic folks in our lab and inspiring collaborators, including Michael Kharas MSK, Alex Bick, Yash Pershad, Ruslan Soldatov, Abdel-Wahab Lab. Please check it out 👇👇