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The RNA Atlas, a single nucleotide resolution map of the human transcriptome biorxiv.org/content/10.110…

This is very sad news. Judy was an extraordinary scientist, a driving force for the field of cellular senescence and a role-model for many of us. She will be greatly missed😢

🔬#Chemotherapy becomes more efficient when senescent cells are eliminated by #immunotherapy. ✍️José Alberto López, #SelimChaib, #ManuelSerrano et al. 📰Nature Cancer 📌DOI:10.1038/s43018-023-00712-x ➡️shorturl.at/frKN5 #IRBScience #AgingResearch #CancerResearch

Today we publish at @Naturecancer our research performed in a joint effort from IRB Barcelona and Vall d’Hebron Institute of Oncology (VHIO), in a team lead by Manuel Serrano. The efficiency of chemotherapy is limited by PD-L2+ intratumoral senescent cells nature.com/articles/s4301…

The results of the MYCure clinical trials are finally out in Nature Medicine: lnkd.in/dgVJ7fvq. (I open the thread)

Ancient #retroviruses may be to thank for the evolution of vertebrate #myelin tissue—and, by extension, our large, complex brains. Read more in Cell: cell.com/cell/fulltext/… Altos Labs Tanay Ghosh, Robin J.M. Franklin

Our new article reveals that gene therapy-mediated partial reprogramming extends lifespan and reverses age-related changes in aged mice, showcasing lifespan extension in wild-type animals through in vivo reprogramming. Noah Carolina Cano M Rejuvenate Bio liebertpub.com/doi/10.1089/ce…

Amazing work by Irvinh Weissman lab Standford University showing how to rejuvenate aged immune system using depleting antibodies to restore balance of blood stem cells. Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity | Nature nature.com/articles/s4158…

When a lab submits a study is a day to celebrate! I share here a fantastic story where we unveiled that DNA damage promotes an MDM2-NICD axis with strong clinical implications. See our manuscript for details and don’t hesitate to comment it. Please RT biorxiv.org/content/10.110…

📡Calling all #sORFs #microproteins #noncanonicaltranslation enthusiasts: don’t miss this upcoming GRC conference dedicated to Microproteins in the amazing Barcelona👇👇👇

Our paper on Nanojaggs to detect senescence in vivo is finally out!! Many thanks Andrew Baker, our collaborators in Fruk Lab, Sarah Bohndiek and a fantastic team!!👇 onlinelibrary.wiley.com/doi/10.1002/an…

Our paper on NanoJaggs to detect senescence in vivo in collaboration with Ljiljana Fruk is finally out!! Many thanks Andrew Baker, our collaborators in@FrukLab, Sarah Bohndiek and a fantastic team!!👇 onlinelibrary.wiley.com/doi/10.1002/an…

Happy to see this story out in Nature Communications. Congratulations Puri Muñoz, Laura Lorenzo and team!🎉

Congrats Marta, Alba and team! Really interesting work on the potential of the microproteome to generate anti-cancer vaccines!

Very proud! Huge congrats to Anna & Thanos, thanks to Raquel Perez-Lopez for her continued trust, and to all collaborators - MANEL ESCOBAR AMORES Paolo Nuciforo Nuria Roson María Abad Alba Escriche Xavier Merino Kinga Bernatowicz @ElenaGarralda Dmitry Novikov Els Fieremans MarcoPalombo et al

I am very happy to share with all of you our new pre-print bioRxiv Cancer Bio from VT lab UPV/EHU- Biokimika eta Biologia Molekularra Saila UPV/EHU “Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer (PCa)”. I open 🧵 (1/5)...

Wonderful opening lecture by María Abad, "The hidden microproteome as a source of novel exosome-secreted extracellular messengers" 👏

Hurray!!!! 🍾🎉🎆 New paper published in a joint effort between Muñoz-Espín Lab from Early Cancer Institute, University of Cambridge and ColladoLab from Instituto de Invest. Sanitaria de Santiago (IDIS). Collaborations make Science and Research better!!! 👇

Amazing ribosomes and... incredible cytokines 😯👇 P-stalk ribosomes act as master regulators of cytokine-mediated processes: Cell cell.com/cell/fulltext/…

Look at this interesting work from Maraver Lab! FMO as a novel target for lung cancer. Congrats to the whole team! 👇🏻👇🏻