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SMG1 is a giant #kinase of the PIKK family & required for #mRNA surveillance. This #cryoEM structure of human SMG1 reveals an unexpected & functionally important ligand that is also conserved in #mTOR & possibly other PIKK family members. Read more ➡️ ow.ly/nWwu50xp4ge

Rapid detection of SARS-CoV-2 by pulse-controlled amplification (PCA) medrxiv.org/cgi/content/sh… #medRxiv

Happy to see this online 😀🧬doi.org/10.1016/j.jvir…

Chemoenzymatic tools developed by Max Fottner et al. allow generating tailormade chains of ubiquitin and ubiquitin-like modifiers to study their specific biological roles Kathrin Lang go.nature.com/3pBRBEC

Happy that our recent Ubl-tools article was featured as an editors’ highlights within “Structural biology, biochemistry and biophysics” Nature Communications nature.com/collections/hh… Congrats Max Fottner Maria Weyh Stefan Gaussmann Dominic Schwarz and @Michael13120606 ! Kathrin Lang 🥳🥂

Very proud of our first year PhD student Maria Weyh who spends this week at the Lindau Nobel Laureate Meetings meeting #LINO22. Have a good time and come back all motivated for new discoveries! 🤩🧪👩‍🔬

Check out our new paper for site-specific labeling proteins and building defined Ub/Ubl-protein conjugates using a plant Asp-endopeptidase. Great effort by Max Fottner @jhmgrtnr Maximilian Gantz RaMue and TimonNK! Congratulations to all!👩‍🔬👨‍🔬🤩🙌🥳

So glad to see this online 🍾🥂 installation of negatively charged lysine acylations via genetic code expansion 🦠🧪👩‍🔬@ML_Jokisch Max Fottner Kathrin Lang