Whoa. Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus | Nature Medicine nature.com/articles/s4159…

Glad to share our latest paper of human DNA-PK activation thanks to the amazing cryo-EM facility ⁦BiocEM Cambridge⁩ ⁦⁦Cambridge Biochemistry⁩ ! We now have structural insights during the progression from ligand binding through to full PK activation pathway: nature.com/articles/s4159…

'I was expecting the worst when I found out I’d need a liver transplant but the whole experience has been fantastic. I am eternally grateful to UAMS, my donor & the donor’s family.' – Don Rhoads, Benton. FULL STORY ON FB!

Innovative approach masking MHC class I molecules to prevent antibody mediated rejection in an experimental #transplant model is reported in the study by Kervella et al. #TransplantTwitter #OpenAccess bit.ly/449RyCF

Congrats to ⁦Lyle Burdine and team!⁩ inside.uams.edu/news/uams-rece…

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Very interesting new study on leveraging v-beta targeting to induce durable anti tumor immunity. Some really interesting opportunities and may provoke us re-think what makes T cells "tumor-specific". Congrats to the whole team here. science.org/doi/10.1126/sc…

A nice review on the current state of TIL therapy

Merry Christmas! Appreciate those working in the hospital

novel perspective suggesting high sustained energy expenditure may be net protective against cancer | Evolution, Medicine, and Public Health | Oxford Academic academic.oup.com/emph/article/1…

As per SRTR UAMS Transplant ranked: · 1st in Nation on liver tx waitlist survival🏆 · 1st in Nation on post kidney tx survival🏆 · 2nd in Nation getting a liver faster❗️ · 4th in Nation getting a kidney faster❗️ What a year ! UAMS Health ASTS ILTS TTS

Groundbreaking achievement alert! Mass General Transplant performed the world’s 1st successful tx of a genetically modified pig kidney into a living patient! Read the whole story and join us in congratulating the entire transplant team for this incredible feat. massgeneral.org/news/press-rel…

Great news for UAMS. Congratulations to all involved!

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

Great research happening at The American Association of Immunologists (AAI) Happy to be here!

Check out some interesting posters at The American Association of Immunologists (AAI).

jvir.org/article/S1051-…

New paper from our lab in collaboration with the Frett lab describing a highly potent DNAPKcs inhibitor with improved solubility that will allow for better analysis of the therapeutic potential of this inhibitor in vivo. nature.com/articles/s4159…

Congratulations to UTSW Graduate School of Biomedical Sciences faculty member, Dr. Chen!