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Adaptive mutability of colorectal cancers in response to targeted therapies science.sciencemag.org/content/early/…

Ifnα “helps” immune presentation and T cell activation nature.com/articles/s4159…

1. Excited to share our new paper in nature! With over 1000 tumors analyzed by scRNA-seq, we provide a systematic pan-cancer characterization of transcriptional intra-tumor heterogeneity (ITH) nature.com/articles/s4158…

Online Now: Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity dlvr.it/Sq0RlP

Online Now: Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer dlvr.it/Sq2lv9

Our work has been published in Cancer Cell Thanks everyone! Ospedale San Raffaele Fondazione AIRC per la ricerca sul cancro #GeneTherapy #Immunotherapy In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases: Cancer Cell cell.com/cancer-cell/fu…

Online Now: In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases dlvr.it/SxjlRX

Local tumoral delivery of IFNα by macrophages  Fondazione AIRC per la ricerca sul cancro  Mario Leonardo Squadrito. Read our summary here 👉 bit.ly/3u5LsGE