🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Rethink your fixative for immunofluorescence !science.org/doi/10.1126/sc…

It's finally out! Well-done to Dr. Amy Chan and many others from Inflammasome Lab! Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme life-science-alliance.org/content/6/10/e…

Curious about human inflammasome and unique functions they have? Check out our 2 fully-funded PhD positions Biology at York @BBSRCWhiteRose findaphd.com/phds/project/f… findaphd.com/phds/project/f…

My friend and collaborator is growing her lab. If you want to work in a great team and are interested in studying the neuronal basis of vision, check out the opportunity below. careers.umich.edu/job_detail/225… University of Michigan Michigan Medicine Michigan Neuroscience Institute (MNI) 〽️🧠

Excited to be presenting my PhD work tomorrow at the ACDS seminar! Thanks so much for the invite :)

I was absolutely delighted to present my #PhDResearch in the #Neuroimmunology session of #BSI23 today. Thank you so much to everyone in ChronoEpilepsyLab @BrainInflam FutureNeuro Centre and Annie Curtis - Clock Lab RCSI for all of your support ❤️🙏 #epilepsy #immunity #circadian

Delighted to share a new methods paper from Caro and Inflammasome Lab for Live Imaging of Pyroptosis in Primary Murine Macrophages! link.springer.com/protocol/10.10…

New exciting work from the Inflammasome Lab just out! Congratulations to Jared Coombs , @DrAlinaZ , Caro and others! NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome | Science Signaling science.org/doi/10.1126/sc…

Ever wondered how NLRP12 can drive autoinflammation? 👀 In our latest work, we show that NLRP12 is an endogenous inhibitor of NLRP3 inflammasome formation, but disease-causing NLRP12 mutants lose this capacity 🤯

We are looking for a postdoc to join our team Wellcome-Wolfson Institute Experimental Medicine - this is a 3 year MRC funded position to investigate ferritin and inflammasome activation in ARDS in collaboration with Cecilia and Danny McAuley Please apply at shorturl.at/jvPRW DM me for more info! Please RT!

Hi everyone! I’m on the lookout for a new role and would really appreciate your support. I'm particularly interested in chatting with #pharma, #biotech and #CROs about how my #biomedical #research skills may benefit your team. I am based in Brisbane, Australia.

Rinie is an amazing scientist and fantastic person, couldn’t recommend enough!

The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis by Caro, S_Emming, Kate Schroder Inflammasome Lab, and colleagues at UQ News Institute for Molecular Bioscience Max Planck Institute for Infection Biology dlvr.it/T7207W

We report a new chemical #NLRP3 activator, forchlorfenuron. Like the imidazoquinolines, FCF induces the K+ efflux-independent pathway of NLRP3 activation by inducing #mitochondrial damage. Congrats to Caro S_Emming & the Inflammasome Lab team! authors.elsevier.com/a/1j5vC8jWWJxL…

Interested in Caspase and LPS signalling? Looking for a multidisciplinary position with a bit of immunology, biochemistry and host-pathogen interactions? Look no further! Our lab is recruiting a second PDRA funded by Biotechnology and Biological Sciences Research. See details below

🚨Voting is now open for the BrainFacts.org Brain Awareness Video Contest! Our PhD student, Tammy Strickland (She/Her), has made it to the top 10 with her video on circadian rhythms and the brain. Show your support by giving her YouTube video a 👍before Sept 15 youtu.be/kBmhH65nYoI

Excited to share our new review Nature Rev Immunol on #inflammasome components as new therapeutic targets in inflammatory disease 🔥💊 Led by the one and only Inflammasome Lab full text here: rdcu.be/dTqxt

It is out! 🚨 Phosphorous-free bacterial lipids can switch between pro- and anti-inflammatory depending on context!🔬 #Immunology #LipidBiology Pablo Pelegrin Inflammasome Lab A big thanks to the reviewers and editors. It was a laborious but smooth process🥳

#NoTimeToDie! Inflammasome Lab, Holley, Monteleone &co show Nature Immunology that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! nature.com/articles/s4159…

Absolutely stellar work by Caro and Inflammasome Lab 👏 A really inspiring tale of how a curious observation evolved into an astounding story which provides previously unexplored insight into how inflammasome signalling shapes adaptive immune responses! 🎉