Markus Höpfler (@markushopfler) 's Twitter Profile
Markus Höpfler

@markushopfler

Incoming group leader @CRGenomica | Postdoc @MRC_LMB Hegde lab | protein synthesis | RNA decay | tubulin homeostasis

ID: 1302334444238508035

calendar_today05-09-2020 19:55:18

160 Tweet

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Markus Höpfler (@markushopfler) 's Twitter Profile Photo

We usually think of mRNAs carrying the information needed to make a protein (the central dogma...). But how can the encoded protein control the fate of its encoding mRNA? 🤔 Check out our review on the topic 👇 cell.com/molecular-cell…

Haoxi Wu (@haoxi_xiaozzxi) 's Twitter Profile Photo

A subset of polytopic membrane proteins, such as subunits of the GABAA receptor, remains incompletely inserted when translation is terminated. We describe an essential post-translational step that completes insertion of such proteins. nature.com/articles/s4159…

Markus Höpfler (@markushopfler) 's Twitter Profile Photo

Thanks @BeAScientist for highlighting our recent work on tubulin regulation by selective mRNA decay! nature.com/articles/s4157…

Pablo Alcón (@palconh) 's Twitter Profile Photo

After six fantastic years at @MRC_LMB, I'm returning to Denmark to join Molekylærbiologi - Molecular Biology! Starting August 2024, we'll combine biochemistry, cryoEM, and single-molecule imaging to study how DNA damage is recognized and repaired. sites.google.com/view/alconlab

Pablo Alcón (@palconh) 's Twitter Profile Photo

Join us in this adventure in beautiful Aarhus! PhD and postdoc positions available! If you're passionate about DNA repair and structural biology, we have several exciting projects for you. Please contact me for more details, and please share with your colleagues!

Join us in this adventure in beautiful Aarhus! PhD and postdoc positions available! If you're passionate about DNA repair and structural biology, we have several exciting projects for you. Please contact me for more details, and please share with your colleagues!
Pablo Alcón (@palconh) 's Twitter Profile Photo

A reminder that our new lab at Molekylærbiologi - Molecular Biology has a fully funded postdoc position available. Our group integrates biochemistry, cryoEM, and single-molecule imaging to explore the mechanisms of DNA repair complexes. 🧬🔬 sites.google.com/view/alconlab/… Please share with your colleagues!

Markus Höpfler (@markushopfler) 's Twitter Profile Photo

Finally out! We identify the first regulatory step in the tubulin autoregulation pathway: TTC5 is sequestered by free αβ-tubulins to prevent it from ribosome binding. Thanks for a great collaboration with Ivana Gasic and Zhewang Lin! nature.com/articles/s4146…

Ivana Gasic (@ivana_gasic) 's Twitter Profile Photo

Lab’s first paper is out 🥳🍾! We reveal how tubulins regulate the stability of their mRNAs via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors! Markus Höpfler Ana Almeida Lila Oscar UNIGE_en Nature Communications 👇 doi.org/10.1038/s41467…

Hsiu-Chuan Lin (@hsiuchuan_lin) 's Twitter Profile Photo

📢 There are 2 open PhD positions in my group at CRG Barcelona! We are looking for candidates interested in cell fate engineering, gene regulation, and single-cell technologies with experience in both wet/dry labs. Please help spread the word! Apply ➡️ crg.eu/en/content/tra…

Markus Höpfler (@markushopfler) 's Twitter Profile Photo

Apply until 12th of January for the Centre for Genomic Regulation (CRG) international PhD programme! There will be 2 positions in my group with a focus on novel mechanisms of mRNA decay in the context of microtubule regulation. Please RT! crg.eu/en/content/tra…