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We usually think of mRNAs carrying the information needed to make a protein (the central dogma...). But how can the encoded protein control the fate of its encoding mRNA? 🤔 Check out our review on the topic 👇 cell.com/molecular-cell…

Interested in DNA replication and genome integrity? Please apply!!!

A subset of polytopic membrane proteins, such as subunits of the GABAA receptor, remains incompletely inserted when translation is terminated. We describe an essential post-translational step that completes insertion of such proteins. nature.com/articles/s4159…

Great opportunity!

Really great collaboration with the lab of Ivana Gasic to figure out the mechanisms controlling selective tubulin mRNA degradation!

Thanks @BeAScientist for highlighting our recent work on tubulin regulation by selective mRNA decay! nature.com/articles/s4157…

After six fantastic years at @MRC_LMB, I'm returning to Denmark to join Molekylærbiologi - Molecular Biology! Starting August 2024, we'll combine biochemistry, cryoEM, and single-molecule imaging to study how DNA damage is recognized and repaired. sites.google.com/view/alconlab

Join us in this adventure in beautiful Aarhus! PhD and postdoc positions available! If you're passionate about DNA repair and structural biology, we have several exciting projects for you. Please contact me for more details, and please share with your colleagues!

A reminder that our new lab at Molekylærbiologi - Molecular Biology has a fully funded postdoc position available. Our group integrates biochemistry, cryoEM, and single-molecule imaging to explore the mechanisms of DNA repair complexes. 🧬🔬 sites.google.com/view/alconlab/… Please share with your colleagues!

The CRG has an outstanding international PhD programme, do apply!!!

Ready for this week's RNA Club? This Thursday we'll be hosting Markus Höpfler and Murat Sunbul at the Cambridge Biochemistry (Sanger Building) for some interesting talks! Hope to see you there! 🍻🍕🧬Thanks to The RNA Society Lexogen 2BScientific Cambridge Bioscience

Looking forward to being Cambridge RNA Club club again!

Finally out! We identify the first regulatory step in the tubulin autoregulation pathway: TTC5 is sequestered by free αβ-tubulins to prevent it from ribosome binding. Thanks for a great collaboration with Ivana Gasic and Zhewang Lin! nature.com/articles/s4146…

Lab’s first paper is out 🥳🍾! We reveal how tubulins regulate the stability of their mRNAs via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors! Markus Höpfler Ana Almeida Lila Oscar UNIGE_en Nature Communications 👇 doi.org/10.1038/s41467…

Looking forward to sharing and discussing my work Cambridge RNA Club club today! See you later!

📢 There are 2 open PhD positions in my group at CRG Barcelona! We are looking for candidates interested in cell fate engineering, gene regulation, and single-cell technologies with experience in both wet/dry labs. Please help spread the word! Apply ➡️ crg.eu/en/content/tra…

Apply until 12th of January for the Centre for Genomic Regulation (CRG) international PhD programme! There will be 2 positions in my group with a focus on novel mechanisms of mRNA decay in the context of microtubule regulation. Please RT! crg.eu/en/content/tra…