🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The symposium at #ean2023 on the #glymphatic system, sleep and #neurodegeneration opened exciting new possibilities for future treatments, linking sleep quality and brain clearance to potentially modify a range of neurological diseases. Full article 👉 ow.ly/pJYA50P672e

Happy to share the newest version of our software with new functionalities for multilayer network analysis and deep learning!! Highly recommended for anyone interested in brain networks and getting the most out of their connectivity data 🧠

Messages of our meta-analysis of gait studies in normal pressure hydrocephalus #nph: 1. The effect of tap test is stronger 24-48 later 2. VPS improvement is greater than tap test's 3. Gait never normalizes, WE DON'T CURE NPH …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Brilliant discussion today at Karolinska Institutet between @fedetriolo_ & Brenda Penninx on #multimorbidity and #depression in old age. Important PhD thesis that moves the field forward. Congrats Federico!

Could gait analysis solve outstanding issues in clinical management of iNPH? A meta-analysis of published literature reveals the best moment to evaluate responsiveness to tap test. Alfonso Fasano Massimiliano Passaretti loom.ly/aGeaOjg

Thanks to Joana B. Pereira Giovanni Volpe Italy in Sweden for inviting me to the Karolinska Institutet AI meeting. I reported that AI showed similar predictive accuracy of cognitive decline (1 year) in Alzheimer's from EEG & sMRI @ElectrophysPIA Dementia Researcher Sapienza Università di Roma DipFisioFarmSapienza

[Brain stimulation] Guerra et al.: "Transcranial alternating current stimulation (tACS) effects potentially involve the modulation of cerebellar neurons resonating with theta (θ) rhythm." Open access: doi.org/10.1016/j.clin…

🔑 In the general population, the concentration of blood biomarkers of AD varies in relation to multiple chronic diseases.- Martina Valletta #ADPD2024

“Demonstrating body-first and brain-first etiology and vulnerability patterns would offer new strategies for disease modifying drugs development. Early recognizing of phenotypes in prodromal phases for development of prevention strategies.” 🤩 Massimiliano Passaretti #ADPD2024

Can you pick out who has Parkinson's disease from the video using the 'whistle-smile' reflex? Maybe? Frederic Hanes described this sign in 1943. Giulia Paparella and colleagues revisit the observation in a trial of 34 Parkinson's folks versus 34 healthy controls in Movement Disorders Clinical Practice.

Finally out our work on motor compensation in early PD. Great effort of all co-authours Roberto Cilia Matteo Bologna Antonio Strafella

Boom! Cerebrospinal fluid (CSF) flow extends to peripheral nerves. Alexander Ligocki, Ed Scott and colleagues FLORIDA UF Health blow our minds. New paper Science Advances. What will we call it now? Cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Just when

Adaptive/closed-loop #DBS is a fascinating new tool which will likely expand the current list of indications, beyond #Parkinson We used it to understand #orthostatic #tremor during day-to-day conditions but also to stimulate on demand, with better results compared to classic DBS

Study found frailty accelerates up to 9 years before dementia onset and is a key early marker. Frailty was linked to higher dementia risk even when measured years before dementia onset and may represent a target for prevention efforts. ja.ma/4hLFake

🚨 New study in Age and Ageing! 🚨 Our latest research, explores 15-year care transitions in older Swedish adults. Key findings: 🩺 Multimorbidity & slow gait = more care needs. 🏠 Cognitive impairment = higher nursing home placements. 📖 Read: doi.org/10.1093/ageing…

Can we see α-synuclein pathologies like Parkinson's disease using human PET scans? Not quite yet, however this Japanese group took a major step forward, by using a novel imaging agent called C05-05. Endo and colleagues shared their findings in Neuron and Hassen and

Are we getting closer to long-term strategies to extract more benefit from DBS therapies? Spencer and colleagues performed some ‘optogenetically inspired’ human experiments and present to us some intriguing ideas on LTP in their latest article in the journal Brain. Key Points: -