Takeya Masubuchi (@masubuchitakeya) 's Twitter Profile
Takeya Masubuchi

@masubuchitakeya

Assistant Project Scientist @UCSanDiego; #Immunity #Cellbio #Biochemistry #Biophysics #Reconstitution #Microscopy; receptor dynamics and cell communication

ID: 969918415233105926

calendar_today03-03-2018 12:52:25

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101 Following

Enfu Hui (@hui_enfu) 's Twitter Profile Photo

Today we report on eLife - the journal mechanisms by which similar immune checkpoint receptors show different preferences on SHP1/2, and that PD1 has an atypical ITIM. Congrats to Xiaozheng Xu Takeya Masubuchi Thanks Review Commons for reviewing & referring our preprint doi.org/10.7554/eLife.…

Enfu Hui (@hui_enfu) 's Twitter Profile Photo

Thrilled to share our Science Immunology paper! Rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. Kudos to Takeya Masubuchi for leading

Thrilled to share our <a href="/SciImmunology/">Science Immunology</a> paper! Rodent PD-1 is weaker than human PD-1 (reduced ligand binding &amp; signaling) &amp; lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. Kudos to  <a href="/MasubuchiTakeya/">Takeya Masubuchi</a> for leading