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Mascot Newsletter, February 2025: Mascot vs FragPipe: semi-tryptic TMTpro. Characterization of the noncanonical proteome. Mascot Server 3.1 is now available. #proteomics #MassSpec matrixscience.com/nl/202502/news…

Mascot Distiller provides DDA LFQ for Bruker, Sciex, Thermo and Waters instruments. Retention time alignment ("match between runs"); ion mobility (Bruker TIMS); fractionation; optimised peak detection; visualisation; and more. #proteomics #MassSpec matrixscience.com/distiller.html

Mascot Newsletter, March 2025: 50% more identifications in Thermo Proteome Discoverer. Maternal immune activation imprints translational dysregulation (Pedro Rodriguez Cutillas). Mascot's ML adapter framework (US HUPO 2025 poster). #proteomics #MassSpec matrixscience.com/nl/202503/news…

If your computer breaks down, do you know how to restore Mascot? As long as you regularly back up the right directories and files, it's straightfoward and fully described in the online help: matrixscience.com/help/disaster_… #proteomics #MassSpec

Sometimes you need a very large sequence database, e.g. search all proteobacteria proteins. Mascot Server has no size limit. Search a database of hundreds of millions of protein sequences without running out of resources. matrixscience.com/blog/big-datab… #proteomics #MassSpec

Mascot newsletter, April 2025: ASMS User Meeting registration is now open. Competitive displacement of lipoprotein lipase by GPIHBP1. MS2PIP models for Thermo instruments. #proteomics #massspec matrixscience.com/nl/202504/news…

Agilent have published an application note for recommended MassHunter Qualitative Analysis settings when searching DDA peak lists with Mascot Server. We've added it to a new help page for Agilent instruments. matrixscience.com/help/instrumen… #proteomics #MassSpec

Mascot Server ships with MS2Rescore, which is one of many predictive ML tools for proteomics. Follow this new tutorial if you want to add an integration to a different AI/ML system. matrixscience.com/blog/adding-a-… #proteomics #MassSpec

Register now for the Matrix Science Breakfast Meeting at #ASMS2025 on 2nd June: matrixscience.com/workshop.html There is no charge for attending the meeting, but advance registration is required. #proteomics #MassSpec

Mascot newsletter, May 2025: ASMS User Meeting registration is open. Oxygen metabolism in horses. Big databases and large peak lists. matrixscience.com/nl/202505/news… #proteomics #massspec

Register now for the Matrix Science Breakfast Meeting at #ASMS2025 on 2nd June: matrixscience.com/workshop.html There is no charge for attending the meeting, but advance registration is required. #proteomics #MassSpec

When you refine results with Mascot Server and import into Thermo Proteome Discoverer, you should disable MudPIT scoring. This makes the Protein FDR Validator node much happier. matrixscience.com/blog/identify-… #proteomics #MassSpec

Register now for the Matrix Science Breakfast Meeting at #ASMS2025 on 2nd June: matrixscience.com/workshop.html There is no charge for attending the meeting, but advance registration is required. #proteomics #MassSpec

Come see our poster TP 505 today at #ASMS2025 : Customizable machine learning adapter improves LFQ in Mascot Distiller

Pick up a free Matrix Science pen, bag or notebook from #ASMS2025 booth #334 -- while stocks last!

Come see our poster ThP 265 today at #ASMS2025: Machine learning-enabled Mascot Server API improves LFQ in client software like Thermo Proteome Discoverer

Mascot Newsletter, June 2025: Annual user meeting summary and preview of Mascot DIA. ASMS posters using Mascot: forensics, cancer research, food science, fish, ... Matrix Science posters on LFQ and machine learning. matrixscience.com/nl/202506/news… #proteomics #massspec

We are working on Mascot DIA, which is a universal spectrum-centric solution for DIA analysis. What is spectrum-centric searching meant to solve? Find out in our blog: matrixscience.com/blog/the-promi… #proteomics #massspec

Mascot Newsletter, July 2025: Overview of spectrum-centric DIA and Mascot DIA. Metaproteomics of bacterioplankton communities. New pricing tiers for Mascot Server, and price reduction when updating from an old version. matrixscience.com/nl/202507/news… #proteomics #massspec

Peptide identification in spectrum-centric DIA depends on accurate precursor mass. The upcoming version of Mascot Distiller includes a novel algorithm that deduces precursor masses from MS/MS scans. #proteomics #massspec matrixscience.com/blog/youve-got…