We're delighted to share with you that Dr. Squire Booker has been reappointed by the Howard Hughes Medical Institute as HHMI investigator for seven years. Please join us in congratulating Dr. Booker for his outstanding scholarship and contributions.

Excited that our recent work on the site-selective labeling of FeMoco is out on the chemrxiv! Big thanks to Dan and Soop Srisantitham. Also thanks to our collaborators, Dmitriy and Brian, for their work on the collecting the beautiful 57Fe ENDOR data. doi.org/10.26434/chemr…

Get to know C&EN (Chemical & Engineering News) 2021 Black Trailblazer Laura M. K. Dassama whose goal is to develop new sickle cell disease treatments. She talked with Nicholas St. Fleur about her scientific journey: fal.cn/3m5CB #BlackInSTEM #WomenInScience

In honor of his contributions to enzyme chemistry, Squire J. Booker (Squire J. Booker) of Penn State HHMI is being inducted to the National Academy of Sciences following his election in 2019. Watch the #NAS159 livestream: ow.ly/cpu850IU7TF #biochemistry

Viperin is a radical SAM protein that inhibits flaviviruses. But what do viperin-like enzymes do? Lachowicz et al Albert Einstein College of Medicine - Official show these enzymes use the same "ddh-synthase" reaction, pointing to an evolutionarily conserved host defense strategy. pubs.acs.org/doi/10.1021/ac… #tbt

Very excited about our second contribution to ACS Bio & Med Chem Au, which describes studies on a novel system for generating the lipoyl cofactor (i.e. lipoic acid). This system consists of two proteins previously annotated as biotin synthases! pubs.acs.org/doi/pdf/10.102…

Squire J. Booker Looking forward to your talk! You are the closer!!! #ChemistsRock #ChemistryLegacy 🔥🔥🔥

The missing step in the formation of a lipid molecule that allows certain single-celled organisms to survive the most extreme environments on Earth has now been deciphered by a team of #PennState and University of Illinois researchers led by Squire J. Booker. buff.ly/3KgxTbA Penn State BMB

Check out the editorial by Cody Cody Lloyd and me for the 20-year anniversary of radical SAM virtual issue of ACS Bio & Med Chem Au Stuart Conway Afsaneh Lavasanifar ACS Publications Bio & Med Chem Content. Thanks to all the authors who contributed!! pubs.acs.org/doi/10.1021/ac…

Excited to share our group’s work on chemically modifying FeMo-co. Here we report our strategy to selectively enrich one of its seven Fe sites with 57Fe for mechanistic studies of the Mo nitrogenase. Big thanks to Dmitriy, Brian, Dan, and Soop Srisantitham. nature.com/articles/s4155…

My first report from American Progress is out! It's why I think fair analysis would say debt/GDP is rising due to tax cuts and NOT spending. First, the big (and true) claim: without the Bush tax cuts, their extensions, & Trump tax cuts, debt/GDP would be declining. americanprogress.org/article/tax-cu…

MAGA Republicans love to harp about “fiscal responsibility” while giving huge tax breaks to their wealthy friends and campaign donors. A new American Progress report finds the Bush + Trump tax cuts are primarily responsible for the growth in the national debt. americanprogress.org/article/tax-cu…

New e- pathway for radical SAM enzymes: "In this work, we provide evidence that the substrate, in this case, heme, facilitates electron transfer from NADPH to the [4Fe-4S] cluster." From Silakov, Lanzilotta and colleagues UGA Penn State News  pubs.acs.org/doi/10.1021/ac…

McCarthy's proposed budget caps would lead to an immediate cut of 14%-31%, growing to 28%-58% below current services, depending on what happens to defense and VA medical care. That 31% first-year cut would leave appropriators $208 billion in the hole. americanprogress.org/article/budget…

Evidence of Atypical Structural Flexibility of the Active Site Surrounding of an [FeFe] Hydrogenase from Clostridium beijerinkii Penn State Chemistry #FeFeHydrogenase #Clostridium pubs.acs.org/doi/10.1021/ja…

Enzymatic Fluoromethylation Enabled by the S-Adenosylmethionine Analog Te-Adenosyl-L-(fluoromethyl)homotellurocysteine NEW #ASAP by Squire J. Booker, Bo Wang, & co-workers from Penn State Chemistry. Read it here: go.acs.org/5cR

Chemoenzymatic synthesis of 3′-Deoxy-3′,4′-didehydro-cytidine triphosphate (ddhCTP) By Tyler Grove, Lawrence Harris et al Albert Einstein College of Medicine - Official Ferrier Research Institute 🔓 Open access in ACS Bio & Med Chem Au 👉 go.acs.org/5Dd

The College of Sciences has named chemistry Associate Professor Wei-chen Chang as the LORD Corporation Distinguished Scholar. 🥳 Learn how has secured more than $3 million of external funding to support his research. ➡️: ncst.at/xvr050PEvQJ

Congrats to Squire J. Booker for being recently honored with the 2023 Percy L. Julian Award from NOBCChE Official! It recognizes his achievements in pure and/or applied science, as well as dedication over the years in research and commitment to the STEM community. psu.edu/news/eberly-co…

Congrats to Joey Cotruvo (Joey Cotruvo), associate professor of chemistry, who was recently named recipient of the 2024 Eli Lilly Award in Biological Chemistry by the #ACS Division of Biological Chemistry! science.psu.edu/news/cotruvo-r… Penn State Eberly College of Science Penn State #Chemistry