🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Extremely happy to see our story out in Molecular Cell! doi.org/10.1016/j.molc… We show how Ki-67 & pre-rRNA phase separate, gluing mitotic #chromosomes together! 🧼🧬🧲 @EMBL EMBL Heidelberg Uni Heidelberg ISTAustria Cuylen Lab Andela Saric @EllenbergLab

Our paper about TE's regulatory functions using ENCODE data has been published! nature.com/articles/s4146… Ting Wang Cedric🧬➰🧬Feschotte We confirmed TEs contributed 25% of regulatory elements in the human genome. We also investigated how different TEs contributed differently. /1

Scientists 🧬 mutated histone H3.3 K9 and K27 residues in mouse ESCs. They found that H3.3K9 was essential for controlling 🎮 specific distal intergenic regions and for proper H3K27me3 deposition at promoters. Nature Communications | go.nature.com/3XuJaNA

EMBL Researchers & their collaborators discovered a process by which cells prevent the activation of ancient viral sequences in the genome. The study shows experimentally, for the first time, the causal role certain histone sites play in gene repression. embl.org/news/science-t…

Excited to share the latest story from the @arnaud_kr lab EMBL ! Together with Christine Moene we used Single Molecule Footprinting to reveal that RNA Pol II occupancy occurs at surprisingly low-frequency at mammalian promoters! Thread below (⬇️) 1/11

Scientists EMBL have identified key cellular control sites that regulate gene expression and prevent the activation of 'cryptic' genomic regions, including ancient viral sequences EMBL Heidelberg Matteo Trovato

📝Epigenomic heterogeneity as a source of tumour evolution Just out in Nature Reviews Cancer - a piece we wrote with Mathieu Lupien and Marthe LAISNE, a fantastic team work and such a pleasure to exchange & confront ideas on cancer epigenetics. 👉nature.com/articles/s4156…

Thrilled to share our paper now out nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by Andrew Moorman Ellie Benitez, and @f_cambuli from the Karuna Ganesh Lab and @dana_per lab! nature.com/articles/s4158… rdcu.be/dYAVK. A 🧵

Online Now: A genome-wide screen identifies silencers with distinct chromatin properties and mechanisms of repression dlvr.it/TGHjyy

I am looking for postdocs to work across the fields of #CellSignalling and Chromatin. Background in #Bioinformatics #PTMbiology #ERC-funded positions - Reach out if you want to discuss. Apply through the IBFG Postdoc Programm 👇 or please share among potential candidates!

#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. nature.com/articles/s4158… #CancerBiology