🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

capabilities maximalist, diffusion realist timing is critical

A 2nd important recent longevity development that is too-little discussed in the field: The first 2 FDA approved allogeneic stem cell therapies, both in past 2 years. - off-the-shelf - mass-producible - likely relevant for multiple age-related pathologies This is important!

another beautiful glimmer of progress using stem cell-derived cells in the central nervous system with transient immunosuppression to dramatically, durably improve life

Here's what you do: First define the minimum amount of time to build a unit of industrial capacity as the time it takes to move the atoms. (This is similar to Elon's "idiot index" - how long does it take to move the physical components into the configuration for a factory, not

We believe improving the human experience is the most important thing to work on. This should be the goal of technology. And building technologies to interface with the brain is the most direct way of doing so.

Colossal's PR game is absolutely fire. How many edits did they make based on ancient DNA? Dire wolves diverged >5M years ago and have >10M genetic changes from modern wolves. Vast majority of changes don't matter much. Power law. Does 1 edit convert a modern wolf into a

3/ Reduce GMP requirements for Ph 1 and GLP Tox req to be more in line with Australia. The gold plated approach is to make $5-10m GMP CMC investments for your GLP Tox and Ph 1. This is the biggest obstacle to capital efficiency at early stage.

the weight loss pill era has arrived Lilly's valuation up >$60B on Phase 3 data

In 2006, following the identification of microglial chemotaxis to injured sites mediated by ATP , Haynes et al. (nature.com/articles/nn180…), showed that P2RY12 ATP receptors facilitate this microglial chemotactic response🤩 #20YearsInVivoMGImaging

prolonging human cognition will involve a combo of (1) cell therapy (2) brain machine interfaces (3) progressive replacement all have traction and are worth vigorously pursuing great thread by Sierra Lore