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The Lens: Ophthalmology Research Newsletter Key point to include for DRCR Protocol V was that it evaluated mgmt options for pts w/ CI-DME on OCT and very good vision 20/25 or better. Intravitreal anti-VEGF improves vision for pts with CI-DME and visual acuity 20/32 or worse, but V shows initial obs ok for 20/25 or better

This past week, Lilly Wagner and Mayo Clinic Neuro and Mayo Clinic ENT colleagues attended NASBS #NASBS2025. Dr. Wagner spoke on the anterior skull base/orbit panel and discussed indications and techniques for biopsy of inflammatory orbital lesions.

Original investigation by Mayo Clinic in OP-RS: Epidemiological patterns of facial nerve palsy in Olmsted County, MN point to increased incidence of Bell palsy over previous studies. bit.ly/4gNQE4U

For the 7th straight year, Newsweek has named Mayo Clinic the No. 1 hospital in its "World’s Best Hospitals" rankings. “Mayo Clinic’s dedicated staff make this possible,” says CEO @GFarrugiaMDGianrico Read more: mayocl.in/41ko7OH

HUGE shoutout to our amazing Mayo Clinic Department of Ophthalmology residents and fellows! We are thankful for you today and every day.

Check out: Clinical Implications of Ultrasound-Based Morphology in Choroidal Melanoma by Mayo Clinic Department of Ophthalmology’s Lauren A. Dalvin, MD w/ Mayo Clinic Comprehensive Cancer Center.

Mohs micrographic surgery with immunohistochemistry achieves excellent local control rates for periocular melanoma in situ. Per Kerri McInnis-Smith Andrea A. Tooley, MD Lilly Wagner in OP-RS. bit.ly/4bq2XmX

Systemic autoimmune conditions including scleromyxedema should be considered in the workup of occult cystoid macular edema. Per Mayo Clinic case report in Retinal Cases & Brief Reports. w/ Sophie J. Bakri MD bit.ly/3XUmbeL

Matt Starr, M.D. will be presenting later this week at VBS - Vit Buckle Society annual meeting. Dr. Starr will debate if artificial intelligence will be good for the field of retina during Medical Retina Debates on Friday, March 21 at 2:15 p.m. local time. Spoiler alert - it's a yes!

Mayo Clinic Department of Ophthalmology in American Journal of Ophthalmology Case Reports: Potential benefits of topical tacrolimus use for management of conjunctival lymphoid hyperplasia. bit.ly/4ivoldg

Is there a relationship between CYP3A4 phenotype, the gene encoding enzyme that metabolizes exogenous steroids, and the rate of steroid-inducted IOP response? Arthur Sit et al evaluates in Journal of Glaucoma. bit.ly/4iHBxvE

Newer #Ophthalmology podcast episodes on advocacy, cyber and emergency risk management, and pediatric ophthalmology research are posted! Are you caught up # Ophthotwitter? bit.ly/4i1MM0C

Developing & validating machine learning models to predict choroidal nevus transformation to melanoma based on multimodel imaging & initial presentation in @AAOJournal’s Ophthalmology Science. w/ Prashant Tailor Timothy W. Olsen Lauren A. Dalvin, MD & Wills Eye Hospital bit.ly/4ikb7za

Insights from the first five years of the Prospective Ocular Tumor Study, a source of detailed, longitudinal data on rare ocular tumors. Published in Seminars in Ophthalmology w/ Lauren A. Dalvin, MD bit.ly/4lLJUIt

The Mayo Clinic Department of Ophthalmology Ophthalmology Residency draws trainees from diverse backgrounds, family status, and professional and personal interests. Learn more about some of our PGY-1 residents’ experiences so far: mayocl.in/4cVlCHT w/ Andrea A. Tooley, MD

Female representation is growing each year in ophthalmology, but women are still underrepresented overall. Sophie J. Bakri MD in American Journal of Ophthalmology describes the geographic variation of gender disparities in #Ophthalmology throughout the US. bit.ly/4k6nJem

Ruti Sella, M.D.’s recent research analyzed currently available AI-driven IOL calculation formulas, together with established formulas. Different formulas were compared using current guidelines and novel analysis tools. Read more: mayocl.in/4koAYY7

Subconjunctival delivery of the STC-1 transgene with a vector system may represent a novel treatment strategy for sustained IOP reduction and improved ocular tolerability that also avoids the daily dosing requirements of currently available medications. bit.ly/3H4RaiU

Augmented reality may allow vitreoretinal surgeons to leverage microscope-integrated digital imaging systems to analyze and highlight key retinal anatomic features in real time, possibly improving safety & precision during surgery. Raymond Iezzi MD in JPM_MDPI bit.ly/43v81nP