Europe is facing record outbreaks of West Nile and chikungunya, with Italy hardest hit and climate change driving a ‘new normal’ of mosquito-borne disease. ms.spr.ly/6011s51NB

Older adults with type 1 diabetes may face higher risks for CVD and death than those with type 2 diabetes, mainly due to longer disease duration, a Swedish nationwide cohort study finds. ms.spr.ly/6017s51NR

Older age at kidney replacement therapy initiation, a higher prevalence of physical inactivity, and higher population density are linked to a higher incidence of kidney replacement therapy in Europe. ms.spr.ly/6011s51N5

Martha’s Rule has been introduced in all acute hospitals in England, giving patients and families the right to a rapid second opinion when care concerns arise. ms.spr.ly/6010s5cGj

Bimekizumab is safe and effective and shows sustained clinical benefits in patients with moderate-to-severe hidradenitis suppurativa, a real-world study spanning 48 weeks shows. ms.spr.ly/6016s5cGi

A first-in-human trial shows gene-edited islet cells survived without immunosuppressive drugs, marking a step toward safer type 1 diabetes treatment. ms.spr.ly/6013s5cGL

Tofacitinib demonstrates effectiveness in treating ulcerative colitis-associated peripheral spondyloarthritis. ms.spr.ly/6011s9rMT

Many NHS patients in England remain unable to access the weight-loss jab Mounjaro as funding shortfalls and patchy rollout create uncertainty and unequal care. ms.spr.ly/6018s9rMw

Pericoronary adipose tissue attenuation measured using coronary CT angiography correlates with levels of IL-6 and TNF alpha and the total plaque volume, a study shows. ms.spr.ly/6010s9rMm

Sacubitril-valsartan does not significantly attenuate the adjuvant breast cancer therapy-related ejection fraction decline but appears to prevent chronic myocardial injury and stress, a study shows. ms.spr.ly/6016s9hre

Young patients with systemic lupus erythematosus have increased arterial stiffness compared with matched healthy individuals, a study shows. ms.spr.ly/6019s9hrS

A new malaria vaccine reduces transmission to mosquitoes in a phase 1 trial, offering a potential tool for future elimination strategies. ms.spr.ly/6013s9hrf

Antibody levels after mpox vaccination decline more rapidly than those after natural mpox infection, and people living with HIV show significantly lower seropositivity at 2 years. ms.spr.ly/6013sixN3

European experts now recommend imaging and a lower LDL target of 40 mg/dL for extreme-risk patients, marking a shift towards personalised care. ms.spr.ly/6010sixNp

Patients surviving valvular surgery for infective endocarditis have higher 5- and 10-year mortality rates than their peers from the general population, a study finds. ms.spr.ly/6017sixNl

Complications during the first pregnancy and interpregnancy weight changes are strongly associated with an elevated risk for first-time preeclampsia during the second pregnancy. ms.spr.ly/6017scZuF

Children presenting with premature adrenarche show early signs of metabolic abnormalities, including taller stature and a higher weight for height, a meta-analysis suggests. ms.spr.ly/6014scZuC

Industry pushback and loopholes are stalling the UK’s plan to curb junk food marketing to kids. What will it take for this bold public health move to stick? ms.spr.ly/6017scZRz

Faecal loss of vedolizumab occurs in patients with active ulcerative colitis, with greater loss seen in non-responders than in responders. ms.spr.ly/6012sc9Ri

The incidence of neonatal herpes simplex virus infections in the UK nearly doubled over 15 years, and outcomes remained poor, with both mortality and morbidity being high. ms.spr.ly/6015sc9Rv